Background: Epidemiologic and experimental studies suggest that air pollution such as
diesel exhaust particles (DEPs), one of the important air pollutants, may play a role in the …

Background: Diesel exhaust particles (DEPs) have been implicated in the worldwide
increased incidence of allergic airway disorders over the past century. They can enhance in …

We have previously shown that exposure to diesel exhaust particles (DEPs) stimulates
human airway epithelial cells to secrete the inflammatory cytokines interleukin-8, interleukin …

The involvement of diesel exhaust particles (DEPs) in respiratory diseases was evaluated by
studying their effects on two in vitro models of human airway epithelial cells. The cytotoxicity …

Previous experimental studies have suggested that nasal instillation of diesel exhaust
particles (DEP) can enhance nasal IgE response and cytokine production. However, there is …

Background: An epidemiologic relationship between airway allergic diseases and exposure
to atmospheric pollutants has been demonstrated and suggested to be one factor in the …

Objective: Epidemiological as well as experimental studies suggest that particulate air
pollutants, including diesel exhaust particles (DEP), may play a role in the recent increase of …

Background: Recent evidence suggests that the airways of asthmatics are more susceptible
to adverse effects of air pollutants than the airways of non–asthmatics, but the underlying …

We have previously reported that intratracheal instillation of diesel exhaust particles (DEP)
enhances allergen-induced eosinophilic airway inflammation, local expression of interleukin …

Background: The ability of combustion products, such as diesel exhaust particles (DEPs), to
modulate the immune system has now been firmly established. DEPs can synergize with …