Emodin alleviates bleomycin-induced pulmonary fibrosis in rats
R Guan, X Zhao, X Wang, N Song, Y Guo, X Yan… - Toxicology Letters, 2016 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease with few treatment options and
poor prognosis. Emodin, extracted from Chinese rhubarb, was found to be able to alleviate …
poor prognosis. Emodin, extracted from Chinese rhubarb, was found to be able to alleviate …
[HTML][HTML] Emodin attenuates bleomycin-induced pulmonary fibrosis via anti-inflammatory and anti-oxidative activities in rats
SL Tian, Y Yang, XL Liu, QB Xu - Medical Science Monitor …, 2018 - ncbi.nlm.nih.gov
Background Idiopathic pulmonary fibrosis (IPF) can severely damage lung function, which
may result in death. Emodin is a major ingredient of rhubarb and has been proven to protect …
may result in death. Emodin is a major ingredient of rhubarb and has been proven to protect …
Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation
R Guan, X Wang, X Zhao, N Song, J Zhu, J Wang… - Scientific reports, 2016 - nature.com
Aberrant activation of TGF-β1 is frequently encountered and promotes epithelial-
mesenchymal transition (EMT) and fibroblast activation in pulmonary fibrosis. The present …
mesenchymal transition (EMT) and fibroblast activation in pulmonary fibrosis. The present …
Diosgenin inhibits TGF-β1/Smad signaling and regulates epithelial mesenchymal transition in experimental pulmonary fibrosis
V Dinesh Babu, A Suresh Kumar… - Drug and Chemical …, 2022 - Taylor & Francis
Abstract Idiopathic Pulmonary Fibrosis (IPF) is a grave disease characterized by abnormal
wound healing associated with chronic, progressive, irreversible fatal lung disease, leading …
wound healing associated with chronic, progressive, irreversible fatal lung disease, leading …
EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-β signaling in lung fibroblasts
YJ Li, A Azuma, J Usuki, S Abe, K Matsuda… - Respiratory …, 2006 - Springer
Background Fourteen-membered ring macrolides have been effective in reducing chronic
airway inflammation and also preventing lung injury and fibrosis in bleomycin-challenged …
airway inflammation and also preventing lung injury and fibrosis in bleomycin-challenged …
Daidzein exhibits anti-fibrotic effect by reducing the expressions of Proteinase activated receptor 2 and TGFβ1/smad mediated inflammation and apoptosis in …
Pulmonary fibrosis (PF) is a progressive lethal disorder. In this study, the effect of daidzein, a
soyisoflavone against Bleomycin (BLM) induced PF in rats was elucidated. A single …
soyisoflavone against Bleomycin (BLM) induced PF in rats was elucidated. A single …
Inula japonica ameliorated bleomycin-induced pulmonary fibrosis via inhibiting soluble epoxide hydrolase
Pulmonary fibrosis is a progressive, irreversible, and fatal fibrotic lung disease with a high
mortality and morbidity, and commonly nonresponsive to conventional therapy. Inula …
mortality and morbidity, and commonly nonresponsive to conventional therapy. Inula …
Inhibitory effect of l-mimosine on bleomycin-induced pulmonary fibrosis in rats: role of eIF3a and p27
XW Li, CP Hu, YJ Li, YX Gao, XM Wang… - International …, 2015 - Elsevier
It has also been shown that the decreased expression of eukaryotic translation initiation
factor 3a (eIF3a) by l-mimosine caused cell cycle arrest. Our previous study has found that …
factor 3a (eIF3a) by l-mimosine caused cell cycle arrest. Our previous study has found that …
A Chinese Traditional Therapy for Bleomycin‐Induced Pulmonary Fibrosis in Mice
L Sun, M Mao, Z Yan, C Zuo… - Canadian Respiratory …, 2018 - Wiley Online Library
Pulmonary fibrosis is a chronic and fatal disease of lung tissue with high incidence and
mortality in the world. The exploration of effective treatment for pulmonary fibrosis remains …
mortality in the world. The exploration of effective treatment for pulmonary fibrosis remains …
Combination of Salvia miltiorrhiza and ligustrazine attenuates bleomycin-induced pulmonary fibrosis in rats via modulating TNF-α and TGF-β
C Huang, X Wu, S Wang, W Wang, F Guo, Y Chen… - Chinese Medicine, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF), a chronic, progressive, fibrosing interstitial
lung disease, is associated with extremely poor prognosis, and lacks effective treatment. The …
lung disease, is associated with extremely poor prognosis, and lacks effective treatment. The …