Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease
PR Holland, JL Searcy, N Salvadores… - Journal of Cerebral …, 2015 - journals.sagepub.com
Cerebral small vessel disease (SVD) is a major cause of age-related cognitive impairment
and dementia. The pathophysiology of SVD is not well understood and is hampered by a …
and dementia. The pathophysiology of SVD is not well understood and is hampered by a …
Pre-clinical models of human cerebral small vessel disease: utility for clinical application
AH Hainsworth, JF Brittain, H Khatun - Journal of the neurological sciences, 2012 - Elsevier
Small vessel disease (SVD) is a frequent cause of vascular cognitive impairment (VCI),
encompassing vascular dementia. SVD is characterised by vasculopathy in deep …
encompassing vascular dementia. SVD is characterised by vasculopathy in deep …
Cerebral vascular dysfunctions detected in human small vessel disease and implications for preclinical studies
JM Wardlaw, H Benveniste… - Annual Review of …, 2022 - annualreviews.org
Cerebral small vessel disease (SVD) is highly prevalent and a common cause of ischemic
and hemorrhagic stroke and dementia, yet the pathophysiology is poorly understood. Its …
and hemorrhagic stroke and dementia, yet the pathophysiology is poorly understood. Its …
Alterations of the cerebral cortex in sporadic small vessel disease: a systematic review of in vivo MRI data
Cerebral small vessel diseases of the brain are a major determinant of cognitive impairment
in the elderly. In small vessel diseases, the most easily identifiable lesions, both at post …
in the elderly. In small vessel diseases, the most easily identifiable lesions, both at post …
Do in vivo Experimental Models Reflect Human Cerebral Small Vessel Disease? a Systematic Review
AH Hainsworth, HS Markus - Journal of Cerebral Blood Flow …, 2008 - journals.sagepub.com
Cerebral small vessel disease (SVD) is a major cause of stroke and dementia.
Pathologically, three lesions are seen: small vessel arteriopathy, lacunar infarction, and …
Pathologically, three lesions are seen: small vessel arteriopathy, lacunar infarction, and …
Blood brain barrier breakdown as the starting point of cerebral small vessel disease?-New insights from a rat model
S Schreiber, CZ Bueche, C Garz, H Braun - Experimental & translational …, 2013 - Springer
Cerebral small vessel disease (CSVD, cerebral microangiopathy) leads to dementia and
stroke-like symptoms. Lacunes, white matter lesions (WML) and microbleeds are the main …
stroke-like symptoms. Lacunes, white matter lesions (WML) and microbleeds are the main …
Cerebral small vessel disease: a review of the pathophysiological mechanisms
Y Hannawi - Translational Stroke Research, 2023 - Springer
Cerebral small vessel disease (cSVD) refers to the age-dependent pathological processes
involving the brain small vessels and leading to vascular cognitive impairment, intracerebral …
involving the brain small vessels and leading to vascular cognitive impairment, intracerebral …
Mechanisms of cognitive impairment in cerebral small vessel disease: multimodal MRI results from the St George's cognition and neuroimaging in stroke (SCANS) …
AJ Lawrence, B Patel, RG Morris, AD MacKinnon… - PloS one, 2013 - journals.plos.org
Cerebral small vessel disease (SVD) is a common cause of vascular cognitive impairment. A
number of disease features can be assessed on MRI including lacunar infarcts, T2 lesion …
number of disease features can be assessed on MRI including lacunar infarcts, T2 lesion …
Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease
A Joutel, M Monet-Leprêtre, C Gosele… - The Journal of …, 2010 - Am Soc Clin Investig
Cerebral ischemic small vessel disease (SVD) is the leading cause of vascular dementia
and a major contributor to stroke in humans. Dominant mutations in NOTCH3 cause cerebral …
and a major contributor to stroke in humans. Dominant mutations in NOTCH3 cause cerebral …
[HTML][HTML] Novel imaging techniques in cerebral small vessel diseases and vascular cognitive impairment
Dementia is a global growing concern, affecting over 35 million people with a global
economic impact of over $604 billion US. With an ageing population the number of people …
economic impact of over $604 billion US. With an ageing population the number of people …