[HTML][HTML] Long non-coding RNA TUG1 enhances chemosensitivity in non-small cell lung cancer by impairing microRNA-221-dependent PTEN inhibition

S Guo, L Zhang, Y Zhang, Z Wu, D He, X Li… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Long non-coding RNA taurine up-regulated gene 1 (TUG1) emerges as new players in gene
regulation in several cancers; however, its mechanism of action in non-small cell lung …

[HTML][HTML] Long noncoding RNA TUG1 is a diagnostic factor in lung adenocarcinoma and suppresses apoptosis via epigenetic silencing of BAX

H Liu, G Zhou, X Fu, H Cui, G Pu, Y Xiao, W Sun… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Lung cancer is one of the leading causes of cancer-related mortality, and responds badly to
existing treatment. Thus, it is of urgent need to identify novel diagnostic markers and …

LncRNA TUG1 promotes cisplatin resistance in esophageal squamous cell carcinoma cells by regulating Nrf2

Z Zhang, R Xiong, C Li, M Xu… - Acta Biochimica et …, 2019 - academic.oup.com
Esophageal squamous cell carcinoma (ESCC) is a common malignancy with poor
prognosis. The drug resistance compromises the efficacy of chemotherapy for ESCC. Long …

[HTML][HTML] Long non-coding RNA TUG1 as a potential prognostic biomarker in human cancers: a meta-analysis

PJ Ma, QK Guan, L Meng, N Qin, J Zhao, BZ Jin - Oncotarget, 2017 - ncbi.nlm.nih.gov
LncRNA taurine upregulated gene 1 (TUG1) is reportedly dysregulated in various cancers.
We performed this meta-analysis to clarify the usefulness of TUG1 as a prognostic marker in …

[HTML][HTML] Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2

Y Niu, F Ma, W Huang, S Fang, M Li, T Wei, L Guo - Molecular cancer, 2017 - Springer
Background Taurine upregulated gene1 (TUG1) as a 7.1-kb lncRNA, has been shown to
play an oncogenic role in various cancers. However, the biological functions of lncRNA …

High TUG1 expression is associated with chemotherapy resistance and poor prognosis in esophageal squamous cell carcinoma

L Jiang, W Wang, G Li, C Sun, Z Ren, H Sheng… - Cancer chemotherapy …, 2016 - Springer
Abstract Purpose Long noncoding RNAs (lncRNAs) play critical roles in diverse biological
processes such as tumorigenesis and metastasis. Taurine upregulated gene 1 (TUG1) is a …

[HTML][HTML] Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2

PC Lin, HD Huang, CC Chang, YS Chang, JC Yen… - BMC cancer, 2016 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis,
and lncRNA taurine-upregulated gene 1 (TUG1) has been proven to be associated with …

[HTML][HTML] Molecular mechanisms of TUG1 in the proliferation, apoptosis, migration and invasion of cancer cells

H Zhou, L Sun, F Wan - Oncology letters, 2019 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) are RNA sequences> 200 nucleotides in length that have
no protein‑coding capacity. lncRNAs serve key roles in multiple biological processes, such …

Anticancer potential of TUG1 knockdown in cisplatin-resistant osteosarcoma through inhibition of MET/Akt signalling

Q Zhou, T Hu, Y Xu - Journal of drug targeting, 2020 - Taylor & Francis
Abstract Development of cisplatin (DDP)-resistance is a major challenge that largely limits
the efficacy of chemotherapy for osteosarcoma. LncRNA Taurine up-regulated gene 1 …

[HTML][HTML] Long non‑coding RNA TUG1 promotes the proliferation of colorectal cancer cells through regulating Wnt/β‑catenin pathway

CH Xiao, HZ Yu, CY Guo, ZM Wu… - Oncology …, 2018 - spandidos-publications.com
The long non‑coding RNA taurine up‑regulated gene 1 (TUG1) has been shown to be
dysregulated in various types of malignant cancer; however, its underlying mechanism of …