Characterization of Helicobacter pylori factors that control transformation frequency and integration length during inter‐strain DNA recombination

O Humbert, MS Dorer, NR Salama - Molecular microbiology, 2011 - Wiley Online Library
Helicobacter pylori is a genetically diverse bacterial species, owing in part to its natural
competence for DNA uptake that facilitates recombination between strains. Inter‐strain DNA …

[HTML][HTML] Genome-wide analysis of chromosomal import patterns after natural transformation of Helicobacter pylori

S Bubendorfer, J Krebes, I Yang, E Hage… - Nature …, 2016 - nature.com
Recombination plays a dominant role in the evolution of the bacterial pathogen Helicobacter
pylori, but its dynamics remain incompletely understood. Here we use an in vitro …

[HTML][HTML] Natural Transformation of Helicobacter pylori Involves the Integration of Short DNA Fragments Interrupted by Gaps of Variable Size

EA Lin, XS Zhang, SM Levine, SR Gill, D Falush… - PLoS …, 2009 - journals.plos.org
Helicobacter pylori are gram-negative bacteria notable for their high level of genetic diversity
and plasticity, features that may play a key role in the organism's ability to colonize the …

DprB facilitates inter-and intragenomic recombination in Helicobacter pylori

XS Zhang, MJ Blaser - Journal of bacteriology, 2012 - Am Soc Microbiol
For naturally competent microorganisms, such as Helicobacter pylori, the steps that permit
recombination of exogenous DNA are not fully understood. Immediately downstream of an …

Helicobacter pylori interstrain restriction‐modification diversity prevents genome subversion by chromosomal DNA from competing strains

RA Aras, AJ Small, T Ando, MJ Blaser - Nucleic acids research, 2002 - academic.oup.com
Helicobacter pylori, bacteria that colonize the human gastric mucosa, possess a large
number of genes for restriction‐modification (R‐M) systems, and essentially, every strain …

Recombination and DNA Repair in Helicobacter pylori

MS Dorer, TH Sessler, NR Salama - Annual review of …, 2011 - annualreviews.org
All organisms have pathways that repair the genome, ensuring their survival and that of their
progeny. But these pathways also serve to diversify the genome, causing changes at the …

[HTML][HTML] The nucleotide excision repair (NER) system of Helicobacter pylori: Role in mutation prevention and chromosomal import patterns after natural transformation

C Moccia, J Krebes, S Kulick, X Didelot, C Kraft… - BMC microbiology, 2012 - Springer
Background Extensive genetic diversity and rapid allelic diversification are characteristics of
the human gastric pathogen Helicobacter pylori, and are believed to contribute to its ability …

Effect of Host Species on RecG Phenotypes in Helicobacter pylori and Escherichia coli

J Kang, D Tavakoli, A Tschumi, RA Aras… - Journal of …, 2004 - Am Soc Microbiol
Recombination is a fundamental mechanism for the generation of genetic variation.
Helicobacter pylori strains have different frequencies of intragenomic recombination, arising …

Restriction–modification system differences in Helicobacter pylori are a barrier to interstrain plasmid transfer

T Ando, Q Xu, M Torres, K Kusugami… - Molecular …, 2000 - Wiley Online Library
Helicobacter pylori cells are naturally competent for the uptake of both plasmid and
chromosomal DNA. However, we demonstrate that there are strong barriers to …

[HTML][HTML] Unveiling novel RecO distant orthologues involved in homologous recombination

S Marsin, A Mathieu, T Kortulewski, R Guérois… - PLoS …, 2008 - journals.plos.org
The generation of a RecA filament on single-stranded DNA is a critical step in homologous
recombination. Two main pathways leading to the formation of the nucleofilament have been …