OSTEOSARCOMA IS the most common primary bone malignancy affecting children and
young adults. Their outlook, compared with the results of treatment available 25 years ago …

Only three decades ago, osteosarcoma was considered incurable; treatment options were
greeted with great skepticism and pessimism [1]. The recognition of the efficacy of adjuvant …

Major advances have been achieved in the treatment of osteosarcoma with the discovery of
several chemotherapeutic agents that were active in the disease. These agents comprise …

Over the last 30 years, the prognosis for children and young adults with osteosarcoma has
changed dramatically. Whereas once fewer than 20% of patients were cured by surgery …

Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …

Osteosarcoma is the bone tumor that most commonly affects children, adolescents, and
young adults. Before 1970, treatment primarily included surgical resection. However, the …

The successful treatment of patients with osteosarcoma requires close cooperation within an
experienced multidisciplinary team including pediatric or medical oncologists, surgeons …

Simple Summary Osteosarcoma is the most common malignant bone tumor in children, with
a 5-year survival rate ranging from 70% to 20% depending on the aggressiveness of the …

Osteosarcoma is a rare malignant tumor of bone that produces osteoid. Most tumors arise in
the metaphyses of long bones. At least 80 per cent of patients have subclini-cal metastases …

Abstract Learning Objectives After completing this course, the reader will be able to: Discuss
etiologic and biologic factors in osteosarcoma. Select the appropriate diagnostic work-up for …