Effects of intranasal administration of oxytocin and vasopressin on social cognition and potential routes and mechanisms of action
S Yao, KM Kendrick - Pharmaceutics, 2022 - mdpi.com
Acute and chronic administration of intranasal oxytocin and vasopressin have been
extensively utilized in both animal models and human preclinical and clinical studies over …
extensively utilized in both animal models and human preclinical and clinical studies over …
Delivery of oxytocin to the brain for the treatment of autism spectrum disorder by nasal application
A Tanaka, T Furubayashi, M Arai, D Inoue… - Molecular …, 2018 - ACS Publications
Oxytocin (OXT) is a cyclic nonapeptide, two amino acids of which are cysteine, forming an
intramolecular disulfide bond. OXT is produced in the hypothalamus and is secreted into the …
intramolecular disulfide bond. OXT is produced in the hypothalamus and is secreted into the …
A randomized trial shows dose-frequency and genotype may determine the therapeutic efficacy of intranasal oxytocin
BackgroundThe neuropeptide oxytocin is proposed as a promising therapy for social
dysfunction by modulating amygdala-mediated social-emotional behavior. Although clinical …
dysfunction by modulating amygdala-mediated social-emotional behavior. Although clinical …
Saliva oxytocin measures do not reflect peripheral plasma concentrations after intranasal oxytocin administration in men
DS Quintana, LT Westlye, KT Smerud… - Hormones and …, 2018 - Elsevier
Oxytocin plays an important role in social behavior. Thus, there has been significant
research interest for the role of the oxytocin system in several psychiatric disorders, and the …
research interest for the role of the oxytocin system in several psychiatric disorders, and the …
Could intranasal oxytocin be used to enhance relationships? Research imperatives, clinical policy, and ethical considerations
Building upon animal-model, human preclinical, and clinical findings, we outline a proposal
for the use of oxytocin in the therapeutic neuroenhancement of contemporary romantic …
for the use of oxytocin in the therapeutic neuroenhancement of contemporary romantic …
Intranasal administration for pain: oxytocin and other polypeptides
Pain, particularly chronic pain, remains one of the most debilitating and difficult-to-treat
conditions in medicine. Chronic pain is difficult to treat, in part because it is associated with …
conditions in medicine. Chronic pain is difficult to treat, in part because it is associated with …
Brain oxytocin: how puzzle stones from animal studies translate into psychiatry
V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …
Effects of positive and negative human contacts and intranasal oxytocin on cerebrospinal fluid oxytocin
JL Rault - Psychoneuroendocrinology, 2016 - Elsevier
Despite the popularity of oxytocin (OT) research for its role in social behavior, the
relationship between the social environment and endogenous central OT remains poorly …
relationship between the social environment and endogenous central OT remains poorly …
The potential of nasal oxytocin administration for remediation of autism spectrum disorders
Y Okamoto, M Ishitobi, Y Wada… - CNS & Neurological …, 2016 - ingentaconnect.com
Administration of oxytocin has been proposed as a treatment for the core symptoms of
autism spectrum disorder (ASD), including social-communicative deficit. Previous clinical …
autism spectrum disorder (ASD), including social-communicative deficit. Previous clinical …
Long-term exposure to intranasal oxytocin in a mouse autism model
Oxytocin (OT) is a neuropeptide involved in mammalian social behavior. It is currently in
clinical trials for the treatment of autism spectrum disorder (ASD). Previous studies in healthy …
clinical trials for the treatment of autism spectrum disorder (ASD). Previous studies in healthy …