We have investigated the role of cAMP in NO-and prostanoid-independent relaxations that
are widely attributed to an endothelium-derived hyperpolarizing factor (EDHF). Under …

We have compared the mechanisms that contribute to endothelium-derived hyperpolarizing
factor (EDHF)-type responses induced by ACh and the Ca2+ ionophore A-23187 in the …

Although an endothelium-derived hyperpolarizing factor (EDHF) has often been
hypothesized to underpin vascular relaxations that are independent of nitric oxide (NO) and …

Isolated rings of rabbit jugular vein have been used to test the hypothesis that formation of
cAMP within the endothelial cell contributes to relaxations that are attributable to the …

We have examined the effects of ouabain (1 mM), the gap junction inhibitors, 18α-
glycyrrhetinic acid (100 μM), N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2, 4-dichlorophenyl)-4 …

We have investigated the role of cAMP in nitric oxide (NO)-and prostanoid-independent
vascular relaxations evoked by acetylcholine (ACh) in isolated arteries and perfused ear …

To clarify the mechanisms involved in relaxations mediated by endothelium-derived
hyperpolarizing factor (EDHF), acetylcholine (ACh)-induced endothelium-dependent …

The mechanisms underlying endothelium-dependent hyperpolarizing factor (EDHF) in the
middle cerebral artery (MCA) remain largely unresolved. In particular, very little is known …

Acetylcholine (ACh) evokes endothelium‐dependent hyperpolarization in arterial cells,
presumably through endothelium‐derived hyperpolarizing factor (EDHF). The identity of …

Vascular endothelial cells release a variety of vasorelaxant factors in response to stretch or
to agonists. Attention has mainly focused on two such factors, prostacyclin and nitric oxide …