[HTML][HTML] Elexacaftor/tezacaftor/ivacaftor improves nasal nitric oxide in patients with cystic fibrosis
CO Pioch, N Ziegahn, C Allomba, LM Busack… - Journal of Cystic …, 2024 - Elsevier
Background In health, nitric oxide (NO) shows high concentrations in the upper airways,
while nasal NO (nNO) is significantly lower in patients with sinonasal inflammation, such as …
while nasal NO (nNO) is significantly lower in patients with sinonasal inflammation, such as …
P042 Nasal nitric oxide increases in patients with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor
CO Pioch, SY Graeber, C Allomba… - Journal of Cystic …, 2023 - cysticfibrosisjournal.com
Objectives: In health, nitric oxide (NO) can be measured in high concentrations in the upper
respiratory tract. It has been shown that nasal NO (nNO) is significantly lower in patients with …
respiratory tract. It has been shown that nasal NO (nNO) is significantly lower in patients with …
The impact of ivacaftor on sinonasal pathology in S1251N-mediated cystic fibrosis patients
R Gostelie, I Stegeman, G Berkers, J Bittermann… - PLoS …, 2020 - journals.plos.org
Importance Sinonasal symptoms in patients suffering from cystic fibrosis can negatively
influence the quality of life and sinuses can be a niche for pathogens causing infection and …
influence the quality of life and sinuses can be a niche for pathogens causing infection and …
Reduced nasal nitric oxide production in cystic fibrosis patients with elevated systemic inflammation markers
RK Michl, J Hentschel, C Fischer, JF Beck, JG Mainz - PLoS One, 2013 - journals.plos.org
Background Nitric oxide (NO) is produced within the respiratory tract and can be detected in
exhaled bronchial and nasal air. The concentration varies in specific diseases, being …
exhaled bronchial and nasal air. The concentration varies in specific diseases, being …
Airway nitric oxide production in patients with cystic fibrosis increases with ivacaftor therapy
Introduction: Nitric oxide (NO) plays an important role in the regulation of airway caliber &
host defense against certain bacteria. NO is reduced in cystic fibrosis (CF) airways & NO …
host defense against certain bacteria. NO is reduced in cystic fibrosis (CF) airways & NO …
Effect of highly effective modulator therapy on quality of life in adults with cystic fibrosis
E DiMango, DB Spielman, J Overdevest… - International forum of …, 2021 - Wiley Online Library
Background Elexacaftor/tezacaftor/ivacaftor is a highly effective modulator that improves
function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein …
function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein …
[HTML][HTML] Effect of ivacaftor therapy on exhaled nitric oxide in patients with cystic fibrosis
Airways of patients with cystic fibrosis are deficient for nitric oxide. Low nitric oxide in cystic
fibrosis has been shown to be associated with poor pulmonary function and risk of infection …
fibrosis has been shown to be associated with poor pulmonary function and risk of infection …
Fraction of exhaled nitric oxide increases in children treated with elexacaftor-tezacaftor-ivacaftor
I Martin, F Ratjen, H Grasemann - 2023 - Eur Respiratory Soc
Introduction: Airway nitric oxide (FENO) in people with cystic fibrosis (CF) is lower than
normal and ivacaftor results in an early and sustained increase in FENO in treated …
normal and ivacaftor results in an early and sustained increase in FENO in treated …
Long-term effect of CFTR modulator therapy on airway nitric oxide
H Grasemann, M Klingel, J Avolio… - European …, 2020 - Eur Respiratory Soc
The fraction of exhaled nitric oxide (F eNO) is generally lower in individuals with cystic
fibrosis (CF), compared to healthy controls. Two recent studies reported that the cystic …
fibrosis (CF), compared to healthy controls. Two recent studies reported that the cystic …
Impact of novel CFTR modulator on sinonasal quality of life in adult patients with cystic fibrosis.
JE Douglas, AM Civantos, TB Locke… - … Forum of Allergy & …, 2021 - search.ebscohost.com
Keywords: cystic fibrosis; CFTR modulator; elexacaftor; tezacaftor; ivacaftor; chronic
rhinosinusitis; sinus surgery; SNOT-22 EN cystic fibrosis CFTR modulator elexacaftor …
rhinosinusitis; sinus surgery; SNOT-22 EN cystic fibrosis CFTR modulator elexacaftor …
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