Emerging cancer cell ferroptosis features the direct depletion of glutathione (GSH) and
resultant chemical inhibition on glutathione peroxidase 4 (GPX4) bioactivity, which …

Ferroptosis, an emerging type of cell death found in the past decades, features specifically
lipid peroxidation during the cell death process commonly by iron accumulation …

The nanocatalytic activity of nanozymes provides a vision for tumor treatment. However, the
glutathione (GSH)-related antioxidant defense system (ADS) formed on the basis of …

Inducing ferroptosis has been acknowledged as an emerging strategy to kill drug‐resistant
tumor cells, but how to efficiently induce ferroptosis at the tumor site and enhance its …

Ferroptosis is a new form of regulated cell death with significant therapeutic prospect, but its
application against drug‐resistant tumor cells is challenging due to their ability to effuse …

Recently, nanozymes with peroxidase (POD)-like activity have shown great promise for
ferroptosis-based tumor therapy, which are capable of transforming hydrogen peroxide …

The upregulation of dihydroorotate dehydrogenase (DHODH) redox systems inside tumor
cells provides a powerful shelter against lipid peroxidation (LPO), impeding ferroptosis …

As a rising generation of nanozymes, single atom enzymes show significant promise for
cancer therapy, due to their maximum atom utilization efficiency and well-defined electronic …

Ferroptosis, as a non‐apoptotic cell death pathway, has attracted increasing attention for
cancer therapy. However, the clinical application of ferroptosis‐participated modalities is …

As next-generation artificial enzymes, nanozymes have shown great promise for tumor
catalytic therapy. In particular, their peroxidase-like activity has been employed to catalyze …