[HTML][HTML] MicroRNA and mRNA dysregulation in astrocytes infected with Zika virus

RA Kozak, A Majer, MJ Biondi, SJ Medina, LW Goneau… - Viruses, 2017 - mdpi.com
The Zika virus (ZIKV) epidemic is an ongoing public health concern. ZIKV is a flavivirus
reported to be associated with microcephaly, and recent work in animal models …

Downregulation of Microcephaly-Causing Genes as a Mechanism for ZIKV Teratogenesis: A Meta-analysis of RNA-Seq Studies

JA Gomes, E Sgarioni, TW Kowalski… - Journal of Molecular …, 2023 - Springer
Zika virus (ZIKV) is a neurotropic teratogen that causes congenital Zika syndrome (CZS),
characterized by brain and eye anomalies. Impaired gene expression in neural cells after …

Use of induced pluripotent stem cells (iPSCs) and cerebral organoids in modeling the congenital infection and neuropathogenesis induced by Zika virus

F Majolo, DR Marinowic, AÁ Moura… - Journal of Medical …, 2019 - Wiley Online Library
Infection with Zika virus (ZIKV) was recently demonstrated to be associated with damage to
the central nervous system, especially microcephaly and the Guillain‐Barré syndrome. This …

Forebrain neural precursor cells are differentially vulnerable to Zika virus infection

SM Shelton, AR Soucy, R Kurzion, E Zeldich… - Eneuro, 2021 - eneuro.org
Prenatal exposure to Zika virus (ZIKV) can result in microencephaly and congenital Zika
syndrome, although some brain cells and structures are spared by the virus for unknown …

[HTML][HTML] Role of microglia in the dissemination of Zika virus from mother to fetal brain

P Xu, C Shan, TJ Dunn, X Xie, H Xia… - PLoS neglected …, 2020 - journals.plos.org
Global Zika virus (ZIKV) outbreaks and their link to microcephaly have raised major public
health concerns. However, the mechanism of maternal-fetal transmission remains largely …

[HTML][HTML] Zika virus infects neural progenitors in the adult mouse brain and alters proliferation

H Li, L Saucedo-Cuevas, JA Regla-Nava, G Chai… - Cell stem cell, 2016 - cell.com
Zika virus (ZIKV)-related neuropathology is an important global health concern. Several
studies have shown that ZIKV can infect neural stem cells in the developing brain, but …

[HTML][HTML] Zika Virus and Neuropathogenesis: The Unanswered Question of Which Strain Is More Prone to Causing Microcephaly and Other Neurological Defects

EL King, N Irigoyen - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Despite being perceived to be a relatively innocuous pathogen during its circulation in Africa
in the 20th century, consequent outbreaks in French Polynesia and Latin America revealed …

[HTML][HTML] Zika infection disrupts proteins involved in the neurosensory system

KKM Glover, A Zahedi-Amiri, Y Lao, V Spicer… - Frontiers in Cell and …, 2020 - frontiersin.org
Newly re-emerging viruses are of great global concern, especially when there are no
therapeutic interventions available during the time of an outbreak. There are still no …

[HTML][HTML] Clinical and preclinical evidence for adverse neurodevelopment after postnatal Zika virus infection

J Raper, A Chahroudi - Tropical Medicine and Infectious Disease, 2021 - mdpi.com
Although the Zika virus (ZIKV) typically causes mild or no symptoms in adults, during the
2015− 2016 outbreak, ZIKV infection in pregnancy resulted in a spectrum of diseases in …

Zika virus infects human fetal brain microglia and induces inflammation

FM Lum, DKS Low, Y Fan, JJL Tan… - Clinical Infectious …, 2017 - academic.oup.com
Background. The unprecedented reemergence of Zika virus (ZIKV) has startled the world
with reports of increased microcephaly in Brazil. ZIKV can infect human neural progenitors …