Zika virus infects intermediate progenitor cells and post-mitotic committed neurons in human fetal brain tissues
Zika virus (ZIKV) infection is associated with microcephaly in fetuses, but the pathogenesis
of ZIKV-related microcephaly is not well understood. Here we show that ZIKV infects the …
of ZIKV-related microcephaly is not well understood. Here we show that ZIKV infects the …
Zika infection disrupts proteins involved in the neurosensory system
KKM Glover, A Zahedi-Amiri, Y Lao, V Spicer… - Frontiers in Cell and …, 2020 - frontiersin.org
Newly re-emerging viruses are of great global concern, especially when there are no
therapeutic interventions available during the time of an outbreak. There are still no …
therapeutic interventions available during the time of an outbreak. There are still no …
Protection of ZIKV infection-induced neuropathy by abrogation of acute antiviral response in human neural progenitors
L Liu, Z Chen, X Zhang, S Li, Y Hui, H Feng… - Cell Death & …, 2019 - nature.com
It remains largely unknown how Zika virus (ZIKV) infection causes severe microcephaly in
human newborns. We examined an Asian lineage ZIKV, SZ01, which similarly infected and …
human newborns. We examined an Asian lineage ZIKV, SZ01, which similarly infected and …
[HTML][HTML] Zika virus depletes neural progenitors in human cerebral organoids through activation of the innate immune receptor TLR3
Emerging evidence from the current outbreak of Zika virus (ZIKV) indicates a strong causal
link between Zika and microcephaly. To investigate how ZIKV infection leads to …
link between Zika and microcephaly. To investigate how ZIKV infection leads to …
Zika virus-mediated death of hippocampal neurons is independent from maturation state
C Büttner, M Heer, J Traichel, M Schwemmle… - Frontiers in Cellular …, 2019 - frontiersin.org
Zika virus (ZIKV) infection of pregnant women and diaplazental transmission to the fetus is
linked to the congenital syndrome of microcephaly in newborns. This neuropathology is …
linked to the congenital syndrome of microcephaly in newborns. This neuropathology is …
Zika virus infects human fetal brain microglia and induces inflammation
Background. The unprecedented reemergence of Zika virus (ZIKV) has startled the world
with reports of increased microcephaly in Brazil. ZIKV can infect human neural progenitors …
with reports of increased microcephaly in Brazil. ZIKV can infect human neural progenitors …
Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes
PF Ledur, K Karmirian, CSG Pedrosa, LRQ Souza… - Scientific reports, 2020 - nature.com
Zika virus (ZIKV) has been extensively studied since it was linked to congenital
malformations, and recent research has revealed that astrocytes are targets of ZIKV …
malformations, and recent research has revealed that astrocytes are targets of ZIKV …
Zika infection and the development of neurological defects
FB Russo, P Jungmann… - Cellular …, 2017 - Wiley Online Library
Starting with the outbreak in Brazil, Zika virus (ZIKV) infection has been correlated with
severe syndromes such as congenital Zika syndrome and Guillain‐Barré syndrome. Here …
severe syndromes such as congenital Zika syndrome and Guillain‐Barré syndrome. Here …
Clinical and preclinical evidence for adverse neurodevelopment after postnatal Zika virus infection
J Raper, A Chahroudi - Tropical Medicine and Infectious Disease, 2021 - mdpi.com
Although the Zika virus (ZIKV) typically causes mild or no symptoms in adults, during the
2015− 2016 outbreak, ZIKV infection in pregnancy resulted in a spectrum of diseases in …
2015− 2016 outbreak, ZIKV infection in pregnancy resulted in a spectrum of diseases in …
Zika virus infection leads to demyelination and axonal injury in mature CNS cultures
V Schultz, SL Cumberworth, Q Gu, N Johnson… - Viruses, 2021 - mdpi.com
Understanding how Zika virus (Flaviviridae; ZIKV) affects neural cells is paramount in
comprehending pathologies associated with infection. Whilst the effects of ZIKV in neural …
comprehending pathologies associated with infection. Whilst the effects of ZIKV in neural …