Finding clues for congenital Zika syndrome: Zika virus selective infection of immature neurons

AM Maestre, A Fernández-Sesma - EBioMedicine, 2016 - thelancet.com
Since the World Health Organization (WHO) declared a Public Health Emergency of
International Concern (PHEIC) in February 2016, due to the suspicion of a link between Zika …

[HTML][HTML] Zika virus infection induces cranial neural crest cells to produce cytokines at levels detrimental for neurogenesis

NL Bayless, RS Greenberg, T Swigut, J Wysocka… - Cell host & …, 2016 - cell.com
Zika virus (ZIKV) infection during pregnancy is linked to microcephaly, which is attributed to
infection of developing brain structures. ZIKV infects neural progenitor cells in vitro, though …

[HTML][HTML] Zika Virus (ZIKV): a review of proposed mechanisms of transmission and associated congenital abnormalities

SK Desai, SD Hartman, S Jayarajan, S Liu… - American journal of …, 2017 - ncbi.nlm.nih.gov
Zika virus (ZIKV) has been of major international public health concern following large
outbreaks in the Americas occurring in 2015-2016. Most notably, ZIKV has been seen to …

[HTML][HTML] Genome-wide integrative analysis of Zika-virus-infected neuronal stem cells reveals roles for microRNAs in cell cycle and stemness

JW Dang, SK Tiwari, Y Qin, TM Rana - Cell reports, 2019 - cell.com
Zika virus (ZIKV) infection is implicated in severe fetal developmental disorders, including
microcephaly. MicroRNAs (miRNAs) post-transcriptionally regulate numerous processes …

Inhibition of innate immune response ameliorates Zika virus-induced neurogenesis deficit in human neural stem cells

P Xu, J Gao, C Shan, TJ Dunn, X Xie… - PLoS neglected …, 2021 - journals.plos.org
Global Zika virus (ZIKV) outbreaks and their strong link to microcephaly have raised major
public health concerns. ZIKV has been reported to affect the innate immune responses in …

The impact of Zika virus infection on human neuroblastoma (SH-SY5Y) cell line

N Luplertlop, S Suwanmanee… - Journal of vector …, 2017 - journals.lww.com
Methods: ZIKV growth kinetics, viral toxicity, and SH-SY5Y cell vialibity were determined
after ZIKV infection in SH-SY5Y cells in vitro. ZIKV-infected SH-SY5Y cells were …

ZIKAVID—Zika virus infection database: a new platform to analyze the molecular impact of Zika virus infection

RL Rosa, L Santi, M Berger, EF Tureta… - Journal of …, 2020 - Springer
The recent outbreak of Zika virus (ZIKV) in Brazil and other countries globally demonstrated
the relevance of ZIKV studies. During and after this outbreak, there was an intense increase …

The African Zika virus MR-766 is more virulent and causes more severe brain damage than current Asian lineage and dengue virus

Q Shao, S Herrlinger, YN Zhu, M Yang… - …, 2017 - journals.biologists.com
The Zika virus (ZIKV) has two lineages, Asian and African, and their impact on developing
brains has not been compared. Dengue virus (DENV) is a close family member of ZIKV and …

Zika virus targets multiple tissues and cell types during the first trimester of pregnancy

N Jabrane-Ferrat, F Veas - Zika Virus: Methods and Protocols, 2020 - Springer
The 2016 Zika virus (ZIKV) outbreak in the Americas has been characterized by an
increased association frequency of fetal neuropathological abnormalities. To have a …

Fetal brain infection is not a unique characteristic of Brazilian Zika viruses

YX Setoh, NY Peng, E Nakayama, AA Amarilla… - Viruses, 2018 - mdpi.com
The recent emergence of Zika virus (ZIKV) in Brazil was associated with an increased
number of fetal brain infections that resulted in a spectrum of congenital neurological …