Advancements in the immunopathogenesis of psoriasis have identified interleukin (IL)‐23
and IL‐17 as fundamental contributors in the immune pathways of the disease. Leveraging …

Introduction: A growing amount of data supporting the pathogenic role of the IL-23/IL-17 axis
in inflammatory/autoimmune disorders has provided the rationale to target the system for …

The pathogenic mechanisms of specific immune-mediated inflammatory diseases (IMIDs)
are not fully understood, but are thought to involve activated T cells with the release of pro …

Psoriatic arthritis (PsA) is a chronic and progressive inflammatory arthritis intimately
associated with psoriasis, and can be an impairing disease that leads to reduced quality of …

Experimental evidence points to the importance of the cytokine interleukin‐17A (IL‐17A) in
the pathogenesis of several immunoinflammatory diseases including psoriasis, psoriatic …

Psoriasis and psoriatic arthritis (PsA) are pathophysiological enigmas among rheumatic
diseases. Substantial clinical advances have been made with new therapy targeting …

The cytokines of the interleukin 17 (IL-17) family play a central role in the control of
infections, especially extracellular fungi. Conversely, if unrestrained, these inflammatory …

Introduction: Psoriasis is a chronic inflammatory skin disease whose pathogenesis is driven
by multiple cytokine-mediated pathways. In this immunologic setting, the centrality of the IL …

ABSTRACT Introduction: Interleukin-17 (IL-17) is a proinflammatory cytokine considered to
play a significant role in the immunopathogenesis of plaque psoriasis. As a result, focus in …

Plaque psoriasis is one of the most common autoimmune skin diseases and is characterized
by erythematous, scaly plaques. Many highly effective, targeted therapies have been …