Background and aims: Cortisol is the final product of the hypothalamus–pituitary–adrenal
(HPA) axis. It is secreted in a pulsatile fashion that displays a circadian rhythm. Infants are …

The hypothalamic–pituitary–adrenal (HPA)-axis is a central component of the body's
neuroendocrine response to stress. Its major end-product cortisol has profound effects on …

Background Most studies on cortisol have focused on smaller, selected samples. We
therefore aimed to sex-specifically study the diurnal cortisol pattern and explore its …

Stress and stress-related concomitants, including hypothalamic-pituitary-adrenal (HPA) axis
activation, are implicated in obesity and its attendant comorbidities. Little is known about this …

Background: Late-night salivary cortisol (LNSC) is one of the most reliable tests to screen for
endogenous Cushing syndrome. This test is simple, inexpensive and noninvasive and has …

Objective To examine associations of hair cortisol concentration (HCC) in mid‐childhood
and change in HCC from mid‐childhood to early adolescence (ΔHCC) with early adolescent …

Background Blunted diurnal cortisol variation has been associated with overt cardiovascular
disease in adults. The relationship between the diurnal cortisol variation and subclinical …

Little is known about the relationship between diurnal cortisol secretion patterns and
cognitive function early in life. This population-based study examined whether diurnal …

Compliance with awakening salivary sampling is important for precise measurement of the
diurnal cortisol profile. During childhood and adolescence, developmental factors influence …

Background Early childhood multiple or persistent regulatory problems (RPs; crying,
sleeping, or feeding problems) have been associated with a risk of behavioural problems in …