Extracellular/microenvironmental redox state
L Chaiswing, TD Oberley - Antioxidants & redox signaling, 2010 - liebertpub.com
Extracellular redox (reduction–oxidation) state is a factor that serves as an important
regulator of cell–microenvironmental interactions and is determined by several known …
regulator of cell–microenvironmental interactions and is determined by several known …
Redox metabolism and malignancy
CL Grek, KD Tew - Current opinion in pharmacology, 2010 - Elsevier
Redox balance underlies cellular homeostasis. Cancer initiation and progression has been
linked to the disruption of redox balance and oxidative stress. Recent findings exemplify the …
linked to the disruption of redox balance and oxidative stress. Recent findings exemplify the …
The relationship of redox with hallmarks of cancer: the importance of homeostasis and context
F Xing, Q Hu, Y Qin, J Xu, B Zhang, X Yu… - Frontiers in …, 2022 - frontiersin.org
Redox homeostasis is a lifelong pursuit of cancer cells. Depending on the context, reactive
oxygen species (ROS) exert paradoxical effects on cancers; an appropriate concentration …
oxygen species (ROS) exert paradoxical effects on cancers; an appropriate concentration …
The tumorigenic roles of the cellular REDOX regulatory systems
SA Castaldo, JR Freitas, NV Conchinha… - Oxidative medicine …, 2016 - Wiley Online Library
The cellular REDOX regulatory systems play a central role in maintaining REDOX
homeostasis that is crucial for cell integrity, survival, and proliferation. To date, a substantial …
homeostasis that is crucial for cell integrity, survival, and proliferation. To date, a substantial …
Reductive stress, bioactive compounds, redox-active metals, and dormant tumor cell biology to develop redox-based tools for the treatment of cancer
JL Quiles, C Sánchez-González… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Cancer is related to redox biology from many points of view, such as initiation
and promotion, metabolism and growth, invasion and metastasis, vascularization, or through …
and promotion, metabolism and growth, invasion and metastasis, vascularization, or through …
Redox regulation and its emerging roles in stem cells and stem-like cancer cells
MA Ogasawara, H Zhang - Antioxidants & redox signaling, 2009 - liebertpub.com
The existence of cancer stem cells has impelled the pursuit to understanding and
characterizing this subset of cells, which are thought to be responsible for tumor recurrence …
characterizing this subset of cells, which are thought to be responsible for tumor recurrence …
Redox imbalance and biochemical changes in cancer
TC Jorgenson, W Zhong, TD Oberley - Cancer research, 2013 - AACR
For this article, we explore a hypothesis involving the possible role of reduction/oxidation
(redox) state in cancer. We hypothesize that many modifications in cellular macromolecules …
(redox) state in cancer. We hypothesize that many modifications in cellular macromolecules …
[HTML][HTML] Redox control of cancer cell destruction
Redox regulation has been proposed to control various aspects of carcinogenesis, cancer
cell growth, metabolism, migration, invasion, metastasis and cancer vascularization. As …
cell growth, metabolism, migration, invasion, metastasis and cancer vascularization. As …
[HTML][HTML] Understanding redox homeostasis and its role in cancer
When a cell is damaged or altered without repair to its system, it usually dies. But if such
damaged or unrepaired cells do not die and proliferate with uncontrolled growth; a mass of …
damaged or unrepaired cells do not die and proliferate with uncontrolled growth; a mass of …
Redox regulation by intrinsic species and extrinsic nutrients in normal and cancer cells
▪ Abstract Cells in multicellular organisms are exposed to both endogenous oxidative
stresses generated metabolically and to oxidative stresses that originate from neighboring …
stresses generated metabolically and to oxidative stresses that originate from neighboring …