Extracellular redox (reduction–oxidation) state is a factor that serves as an important
regulator of cell–microenvironmental interactions and is determined by several known …

Redox balance underlies cellular homeostasis. Cancer initiation and progression has been
linked to the disruption of redox balance and oxidative stress. Recent findings exemplify the …

Redox homeostasis is a lifelong pursuit of cancer cells. Depending on the context, reactive
oxygen species (ROS) exert paradoxical effects on cancers; an appropriate concentration …

The cellular REDOX regulatory systems play a central role in maintaining REDOX
homeostasis that is crucial for cell integrity, survival, and proliferation. To date, a substantial …

Significance: Cancer is related to redox biology from many points of view, such as initiation
and promotion, metabolism and growth, invasion and metastasis, vascularization, or through …

The existence of cancer stem cells has impelled the pursuit to understanding and
characterizing this subset of cells, which are thought to be responsible for tumor recurrence …

For this article, we explore a hypothesis involving the possible role of reduction/oxidation
(redox) state in cancer. We hypothesize that many modifications in cellular macromolecules …

Redox regulation has been proposed to control various aspects of carcinogenesis, cancer
cell growth, metabolism, migration, invasion, metastasis and cancer vascularization. As …

When a cell is damaged or altered without repair to its system, it usually dies. But if such
damaged or unrepaired cells do not die and proliferate with uncontrolled growth; a mass of …

▪ Abstract Cells in multicellular organisms are exposed to both endogenous oxidative
stresses generated metabolically and to oxidative stresses that originate from neighboring …