[HTML][HTML] Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism
TRS Matthews-Palmer, N Gonzalez-Rodriguez… - Journal of structural …, 2021 - Elsevier
Bacterial type III secretion systems assemble the axial structures of both injectisomes and
flagella. Injectisome type III secretion systems subsequently secrete effector proteins through …
flagella. Injectisome type III secretion systems subsequently secrete effector proteins through …
Cryo-EM analysis of the SctV cytosolic domain from the enteropathogenic E. coli T3SS injectisome
DD Majewski, BJE Lyons, CE Atkinson… - Journal of structural …, 2020 - Elsevier
The bacterial injectisome and flagella both rely on type III secretion systems for their
assembly. The syringe-like injectisome creates a continuous channel between the bacterium …
assembly. The syringe-like injectisome creates a continuous channel between the bacterium …
SsaV Interacts with SsaL to Control the Translocon-to-Effector Switch in the Salmonella SPI-2 Type Three Secretion System
Nonflagellar type III secretion systems (nf T3SSs) form a cell surface needle-like structure
and an associated translocon that deliver bacterial effector proteins into eukaryotic host …
and an associated translocon that deliver bacterial effector proteins into eukaryotic host …
Conserved salt bridges facilitate assembly of the helical core export apparatus of a Salmonella enterica Type III secretion system
N Singh, T Kronenberger, A Eipper, F Weichel… - Journal of Molecular …, 2021 - Elsevier
Virulence-associated type III secretion systems (T3SS) are utilized by Gram negative
bacterial pathogens for injection of effector proteins into eukaryotic host cells. The …
bacterial pathogens for injection of effector proteins into eukaryotic host cells. The …
Structural and functional analysis of SsaV cytoplasmic domain and variable linker states in the context of the InvA-SsaV chimeric protein
J Xu, J Wang, A Liu, Y Zhang, X Gao - Microbiology Spectrum, 2021 - Am Soc Microbiol
The type III secretion (T3S) injectisome is a syringe-like protein-delivery nanomachine
widely utilized by Gram-negative bacteria. It can deliver effector proteins directly from …
widely utilized by Gram-negative bacteria. It can deliver effector proteins directly from …
The structures of SctK and SctD from Pseudomonas aeruginosa reveal the interface of the type III secretion system basal body and sorting platform
M Muthuramalingam, SK Whittier, S Lovell… - Journal of molecular …, 2020 - Elsevier
Many Gram-negative bacterial pathogens use type III secretion systems (T3SS) to inject
proteins into eukaryotic cells to subvert normal cellular functions. The T3SS apparatus …
proteins into eukaryotic cells to subvert normal cellular functions. The T3SS apparatus …
Substrate-engaged type III secretion system structures reveal gating mechanism for unfolded protein translocation
S Miletic, D Fahrenkamp, N Goessweiner-Mohr… - Nature …, 2021 - nature.com
Many bacterial pathogens rely on virulent type III secretion systems (T3SSs) or injectisomes
to translocate effector proteins in order to establish infection. The central component of the …
to translocate effector proteins in order to establish infection. The central component of the …
Role of autocleavage in the function of a type III secretion specificity switch protein in Salmonella enterica serovar Typhimurium
JV Monjarás Feria, MD Lefebre, YD Stierhof, JE Galán… - MBio, 2015 - Am Soc Microbiol
Type III secretion systems (T3SSs) are multiprotein machines employed by many Gram-
negative bacteria to inject bacterial effector proteins into eukaryotic host cells to promote …
negative bacteria to inject bacterial effector proteins into eukaryotic host cells to promote …
Structural insights into the assembly of the type III secretion needle complex
TC Marlovits, T Kubori, A Sukhan, DR Thomas… - Science, 2004 - science.org
Type III secretion systems (TTSSs) mediate translocation of virulence factors into host cells.
We report the 17-angstrom resolution structures of a central component of Salmonella …
We report the 17-angstrom resolution structures of a central component of Salmonella …
The inner rod of virulence‐associated type III secretion systems constitutes a needle adapter of one helical turn that is deeply integrated into the system's export …
CE Torres‐Vargas, T Kronenberger… - Molecular …, 2019 - Wiley Online Library
Type III secretion injectisomes are essential virulence factors for many pathogenic bacteria
by mediating the transport of effector proteins into eukaryotic host cells. The secretion …
by mediating the transport of effector proteins into eukaryotic host cells. The secretion …