Osteosarcoma treatment: state of the art

HT Ta, CR Dass, PFM Choong, DE Dunstan - Cancer and Metastasis …, 2009 - Springer
Osteosarcoma (OS) is a class of cancer originating from bone, mainly afflicting children or
young adults. It is the second highest cause of cancer-related death in these age groups …

The current and future therapies for human osteosarcoma

JD Lamplot, S Denduluri, J Qin, R Li… - Current cancer …, 2013 - ingentaconnect.com
Osteosarcoma (OS) is the most common non-hematologic malignant tumor of bone in adults
and children. As sarcomas are more common in adolescents and young adults than most …

Origin and therapies of osteosarcoma

B Moukengue, M Lallier, L Marchandet, M Baud'huin… - Cancers, 2022 - mdpi.com
Simple Summary Osteosarcoma is the most common malignant bone tumor in children, with
a 5-year survival rate ranging from 70% to 20% depending on the aggressiveness of the …

Current therapeutic strategies and novel approaches in osteosarcoma

K Ando, MF Heymann, V Stresing, K Mori, F Rédini… - Cancers, 2013 - mdpi.com
Osteosarcoma is the most frequent malignant primary bone tumor and a main cause of
cancer-related death in children and adolescents. Although long-term survival in localized …

New targets and approaches in osteosarcoma

J Gill, MK Ahluwalia, D Geller, R Gorlick - Pharmacology & therapeutics, 2013 - Elsevier
Osteosarcoma is the most common primary tumor of bone. Approximately 2/3 of patients
who present with localized osteosarcoma can be expected to be cured of their disease with …

Novel therapeutic agents for osteosarcoma

K O'Day, R Gorlick - Expert review of anticancer therapy, 2009 - Taylor & Francis
Osteosarcoma is the most common malignant primary bone tumor in childhood. Despite
multiagent chemotherapy and aggressive surgical resection, 30% of patients with localized …

Osteosarcoma

HC Beird, SS Bielack, AM Flanagan, J Gill… - Nature reviews Disease …, 2022 - nature.com
Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …

Update on osteosarcoma

R Belayneh, MS Fourman, S Bhogal, KR Weiss - Current oncology reports, 2021 - Springer
Abstract Purpose of Review Osteosarcoma (OSA) is the most common primary tumor of
bone, mainly affecting children and adolescents. Here we discuss recent advances in …

Recent advances in the management of osteosarcoma and forthcoming therapeutic strategies

F Lamoureux, V Trichet, C Chipoy… - Expert review of …, 2007 - Taylor & Francis
Osteosarcoma is the most frequent primary bone tumor and occurs mainly in young patients
(average age: 18 years). No evolution of the survival rates has been recorded for two …

Osteosarcoma: accelerating progress makes for a hopeful future

AJ Saraf, JM Fenger, RD Roberts - Frontiers in oncology, 2018 - frontiersin.org
Patients who develop osteosarcoma in 2017 receive treatment that remains essentially
unchanged since the 1970s. Outcomes likewise remain largely unimproved. Large …