[HTML][HTML] ZEB2 promotes tumor metastasis and correlates with poor prognosis of human colorectal cancer

MZ Li, JJ Wang, SB Yang, WF Li, LB Xiao… - American journal of …, 2017 - ncbi.nlm.nih.gov
Colorectal cancer remains the most common cause of cancer-related deaths worldwide and
it continues to lack an effective treatment. Here, we found that zinc finger E-box binding …

[HTML][HTML] High expression of ZEB1 correlates with liver metastasis and poor prognosis in colorectal cancer

GJ Zhang, T Zhou, HP Tian, ZL Liu… - Oncology …, 2013 - spandidos-publications.com
Zinc finger E-box binding homeobox 1 (ZEB1) has been shown to promote invasion and
metastasis in several types of human cancer and to have a prognostic role in certain …

Overexpression of ZEB2 at the Invasion Front of Colorectal Cancer Is an Independent Prognostic Marker and Regulates Tumor Invasion In Vitro

C Kahlert, S Lahes, P Radhakrishnan, S Dutta… - Clinical cancer …, 2011 - AACR
Purpose: Epithelial-to-mesenchymal transition (EMT) plays a pivotal role in tumor invasion
and dissemination. EMT occurs predominantly at the tumor edge where it is induced by …

Overexpression of zinc finger E-box binding homeobox factor 1 promotes tumor invasiveness and confers unfavorable prognosis in esophageal squamous cell …

X Yang, Q Wang, W Dai, J Zhang, X Chen - Tumor Biology, 2014 - Springer
Zinc finger E-box binding homeobox factor 1 (ZEB1), as a crucial mediator of “epithelial-
mesenchymal transition,” contributes to malignant progression of various epithelial tumors …

ZEB2 promotes the metastasis of gastric cancer and modulates epithelial mesenchymal transition of gastric cancer cells

YH Dai, YP Tang, HY Zhu, L Lv, Y Chu… - Digestive diseases and …, 2012 - Springer
Background Invasion and metastasis are the hallmarks of advanced gastric cancer
progression. Therefore, it is urgent to overcome metastasis in order to improve the survival of …

Overexpression of ZEB1 associated with metastasis and invasion in patients with gastric carcinoma

B Jia, H Liu, Q Kong, B Li - Molecular and cellular biochemistry, 2012 - Springer
The aim of this study was to investigate the expression of ZEB1 in gastric carcinoma, its
correlation with the clinicopathology of gastric carcinoma, and the role of ZEB1 in invasion …

Clinical significance of zinc finger E‐box binding homeobox 1 (ZEB1) in human gastric cancer

Y Okugawa, Y Toiyama, K Tanaka… - Journal of surgical …, 2012 - Wiley Online Library
Abstract Background and Objectives Zinc finger E‐box Binding homeobox 1 (ZEB1)
encodes a transcription factor and is one of the epithelial–mesenchymal transition (EMT) …

USP10 regulates ZEB1 ubiquitination and protein stability to inhibit ZEB1-mediated colorectal cancer metastasis

L Sun, J Yu, J Guinney, B Qin, FA Sinicrope - Molecular Cancer Research, 2023 - AACR
Zinc finger E-box–binding homeobox 1 (ZEB1) is a transcription factor that can promote
tumor invasion and metastasis by inducing epithelial-to-mesenchymal transition (EMT). To …

Regulation of ZEB1 function and molecular associations in tumor progression and metastasis

M Perez-Oquendo, DL Gibbons - Cancers, 2022 - mdpi.com
Simple Summary Given the importance of the epithelial-to-mesenchymal transition in tumor
progression and the pivotal role of ZEB1 as a transcriptional repressor during this process …

[HTML][HTML] ZEB1 promotes tumorigenesis and metastasis in hepatocellular carcinoma by regulating the expression of vimentin

Y Qin, J Yu, M Zhang, F Qin… - Molecular Medicine …, 2019 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide and its
prognosis remains poor. Epithelial‑to‑mesenchymal transition (EMT)‑induced markers have …