Virus-host interactome and proteomic survey of PMBCs from COVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis

J Li, M Guo, X Tian, C Liu, X Wang, X Yang, P Wu… - BioRxiv, 2020 - biorxiv.org
The ongoing coronavirus disease (COVID-19) pandemic caused by Severe Acute
Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a global public health concern due …

Comprehensive analysis of the host-virus interactome of SARS-CoV-2

Z Chen, C Wang, X Feng, L Nie, M Tang, H Zhang… - Biorxiv, 2021 - biorxiv.org
Host-virus protein-protein interaction is the key component of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) lifecycle. We conducted a comprehensive …

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

X Liu, S Huuskonen, T Laitinen, T Redchuk… - Molecular Systems …, 2021 - embopress.org
Abstract Treatment options for COVID‐19, caused by SARS‐CoV‐2, remain limited.
Understanding viral pathogenesis at the molecular level is critical to develop effective …

[HTML][HTML] COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms

M Ostaszewski, A Mazein, ME Gillespie, I Kuperstein… - Scientific data, 2020 - nature.com
COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host
interaction mechanisms | Scientific Data Skip to main content Thank you for visiting nature.com …

[HTML][HTML] Interactome of SARS-CoV-2/nCoV19 modulated host proteins with computationally predicted PPIs

KB Karunakaran, N Balakrishnan… - Research …, 2020 - ncbi.nlm.nih.gov
World over, people are looking for solutions to tackle the pandemic coronavirus disease
(COVID-19) caused by the virus SARS-CoV-2/nCoV-19. Notable contributions in biomedical …

[HTML][HTML] A BioID-derived proximity interactome for SARS-CoV-2 proteins

DG May, L Martin-Sancho, V Anschau, S Liu… - Viruses, 2022 - mdpi.com
The novel coronavirus SARS-CoV-2 is responsible for the ongoing COVID-19 pandemic and
has caused a major health and economic burden worldwide. Understanding how SARS …

Interactome of human and SARS-CoV-2 proteins to identify human hub proteins associated with comorbidities

N Ghosh, I Saha, N Sharma - Computers in Biology and Medicine, 2021 - Elsevier
SARS-CoV-2 has a higher chance of progression in adults of any age with certain
underlying health conditions or comorbidities like cancer, neurological diseases and in …

Understanding individual SARS-CoV-2 proteins for targeted drug development against COVID-19

J van de Leemput, Z Han - Molecular and cellular biology, 2021 - Taylor & Francis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic, responsible for millions of deaths globally. Even with effective vaccines, SARS …

COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms

M Ostaszewski, A Niarakis, A Mazein… - Molecular systems …, 2021 - embopress.org
We need to effectively combine the knowledge from surging literature with complex datasets
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …

Pathogenesis, symptomatology, and transmission of SARS-CoV-2 through analysis of viral genomics and structure

HM Rando, AL MacLean, AJ Lee, R Lordan, S Ray… - …, 2021 - Am Soc Microbiol
The novel coronavirus SARS-CoV-2, which emerged in late 2019, has since spread around
the world and infected hundreds of millions of people with coronavirus disease 2019 …