Acute myeloid leukemia (AML) with the inv (16)/t (16; 16) karyotype is associated with a
favourable prognosis, showing longer periods of complete remission and high overall …

Acute myeloid leukemia (AML) with an inv (16)(p13q22) or t (16; 16)(p13; q22) chromosomal
abnormality represents one of the most common subtypes of de novo cases. These …

The spectrum of CBFB-MYH11 fusion transcripts in acute myeloid leukemia (AML) M4eo
with inv (16)/t (16; 16) is heterogeneous. Approximately 85% show type A CBFB-MYH11 …

Acute myeloid leukemia (AML) with inv (16)(p13. 1q22) resulting in CBFB-MYH11 fusion is
associated with a favorable prognosis. The presence of a KIT mutation modifies it to an …

The leukemia-associated fusion gene CBFB/MYH11 results from a pericentric inversion of
chromosome 16, inv (16)(p13. 1q22), or less commonly from at (16; 16)(p13. 1; q22) …

The inv (16)(p13q22) rearrangement is present in approximately 10% of cases with de novo
acute myeloid leukemia (AML) and results in a CBFB-MYH11 gene fusion. 1 Patients with …

A 77 year-old female was found with FAB M4Eo acute myeloid leukemia. Although CBFB-
MYH11 mRNA was detected in RT-PCR, the conventional cytogenetic analysis failed to …

Coexistence of inv (16) and t (9; 22) is a rare chromosomal aberration, one that has been
described in chronic myelogenous leukemia (CML), mainly in myeloid blast crisis, and de …

Inv (16)(p13q22) and the related translocation t (16; 16)(p13; q22) generate a CBFB-MYH11
fusion gene transcript and are commonly found in acute myeloid leukemia (AML) M4Eo. 1 …

Acute myeloid leukemia (AML) cases with inv (16)(p13q22) or t (16; 16)(p13; q22) are
characterized by multiple CBFB-MYH11 fusion transcripts, type A being the most frequent …