Remarkable progress has been made in the past decade in the treatment and in the
understanding of the biology of childhood lymphoid and myeloid leukemias. With …

PURPOSE: To improve efficacy and reduce toxic-ity of treatment for children with acute
lymphoblas-tic leukemia. PATIENTS AND METHODS: Patients from all risk groups, including …

There has been steady improvement in outcome for children and adolescents with acute
lymphoblastic leukemia (ALL) in the past 40 years. In this decade, we can expect that at …

Abstract St Jude Total Therapy Study XIIIB for childhood acute lymphoblastic leukemia (ALL)
incorporated more stringent risk classification, early intensification of intrathecal …

PURPOSE The goals of this treatment program were as follows: to improve event-free
survival (EFS) rates for high-risk (HR) patients by increasing the intensity of induction …

Abstract Since 1968, the Children's Cancer Group (CCG) has treated more than 16 000
children with acute lymphoblastic leukemia (ALL). Herein, we report improvements obtained …

During the past decade, advances in the treatment of childhood acute lymphoblastic
leukemia (ALL) have continued, largely due to improved disease‐free survival of poor …

Childhood acute lymphoblastic leukemia (ALL) is the most common malignancy of
childhood. Studies in ALL have been a model for clinical and basic research beyond …

This article discusses ways in which pediatric patients with acute lymphoblastic leukemia
(ALL) can be stratified to receive intensive and less intensive therapies in order to decrease …

William L. Carroll, MD and Elizabeth A. Raetz, MD Acute lymphoblastic leukemia (ALL) is the
most common malignancy of childhood, accounting for 25% of cancers diagnosed in …