The major birch pollen allergen Bet v 1 is the main elicitor of airborne type I allergies and
belongs to the PR-10 family (pathogenesis-related proteins 10). Bet v 1 is the most …

Bet v 1 is a 17-kDa protein abundantly present in the pollen of the White birch tree and is the
primary cause of birch pollen allergy in humans. Its three-dimensional structure is …

The term allergy was coined in 1906 by the Austrian scientist and pediatrician Clemens
Freiherr von Pirquet. In 1976, Dietrich Kraft became the head of the Allergy and Immunology …

Background Birch pollen allergy represents the main cause of winter and spring pollinosis in
the temperate climate zone of the northern hemisphere and sensitization towards Bet v 1 …

Bet v 1, the major allergen of birch pollen, displays a considerable degree of heterogeneity.
Several charge variants have been detected by two-dimensional IgE immunoblots and …

Each spring millions of patients suffer from allergies when birch pollen is released into the
air. In most cases, the major pollen allergen Bet v 1 is the elicitor of the allergy symptoms …

Abstract Purpose of Review Pathogenesis-related class 10 (PR-10) proteins are highly
conserved plant proteins, which are induced in response to abiotic and biotic stress factors …

The ability of pathogenesis-related proteins of family 10 to bind a broad spectrum of ligands
is considered to play a key role for their physiological and pathological functions. In …

Bet v I, the major allergen of birch pollen, is a 17 kD cytosolic protein that is quantitatively
extracted from pollen grains by simply washing with water. The cDNA sequence¹ of Bet v I …

Bet v 1, the single major allergen from birch pollen, shares IgE epitopes with all major tree
pollen allergens from closely related species such as alder, hazel, hornbeam, beech, and …