Exercise and adipose tissue immunity: outrunning inflammation

NC Winn, MA Cottam, DH Wasserman, AH Hasty - Obesity, 2021 - Wiley Online Library
Chronic inflammation is considered a precipitating factor and possibly an underlying cause
of many noncommunicable diseases, including cardiovascular disease, metabolic diseases …

Exercise and adipose tissue macrophages: new frontiers in obesity research?

J Goh, KP Goh, A Abbasi - Frontiers in endocrinology, 2016 - frontiersin.org
Obesity is a major public health problem in the twenty-first century. Mutations in genes that
regulate substrate metabolism, subsequent dysfunction in their protein products, and other …

Immune and inflammatory signaling pathways in exercise and obesity

K Krüger, FC Mooren, K Eder… - American journal of …, 2016 - journals.sagepub.com
Over the last decades the combination of both a sedentary lifestyle and excessive food
availability has led to a significant increase in the prevalence of obesity, which is …

[HTML][HTML] Adipose tissue inflammation and metabolic dysfunction: role of exercise

YM Park, M Myers, VJ Vieira-Potter - Missouri medicine, 2014 - ncbi.nlm.nih.gov
Our current environment has led to a vicious cycle of physical inactivity, obesity, and chronic
inflammation, creating the “perfect storm” for metabolic diseases. White adipose tissue …

The exercise training modulatory effects on the obesity-induced immunometabolic dysfunctions

N Soltani, SM Marandi, M Kazemi… - … Syndrome and Obesity, 2020 - Taylor & Francis
Reduced physical activity rate in people's lifestyle is a global concern associated with the
prevalence of health disorders such as obesity and metabolic disturbance. Ample evidence …

The immune system in obesity: developing paradigms amidst inconvenient truths

M Agrawal, PA Kern, BS Nikolajczyk - Current diabetes reports, 2017 - Springer
Abstract Purpose of Review Adipose tissue (AT) houses both innate and adaptive immune
systems that are crucial for preserving AT function and metabolic homeostasis. In this …

Adiposity, immunity, and inflammation: interrelationships in health and disease: a report from 24th Annual Harvard Nutrition Obesity Symposium, June 2023

MF Burak, TL Stanley, EA Lawson, SL Campbell… - The American Journal of …, 2024 - Elsevier
The rapidly evolving field of immunometabolism explores how changes in local immune
environments may affect key metabolic and cellular processes, including that of adipose …

Mechanisms of inflammatory responses in obese adipose tissue

S Sun, Y Ji, S Kersten, L Qi - Annual review of nutrition, 2012 - annualreviews.org
The fields of immunology and metabolism are rapidly converging on adipose tissue. During
obesity, many immune cells infiltrate or populate in adipose tissue and promote a low-grade …

[HTML][HTML] Crosstalk between adipocytes and immune cells in adipose tissue inflammation and metabolic dysregulation in obesity

JY Huh, YJ Park, M Ham, JB Kim - Molecules and cells, 2014 - Elsevier
Recent findings, notably on adipokines and adipose tissue inflammation, have revised the
concept of adipose tissues being a mere storage depot for body energy. Instead, adipose …

Chronic adipose tissue inflammation: all immune cells on the stage

G Cildir, SC Akıncılar, V Tergaonkar - Trends in molecular medicine, 2013 - cell.com
Inflammation is indispensable for host homeostasis against invading pathogens and efficient
wound healing upon tissue malfunction and has to be tightly controlled by various …