The endothelial cell protein C receptor@ PCR) is the most recently identified member O {,
the protein C anticoagulant pathway. Protein C and activaibd protein C (APC) bind to EPCR …

The blood coagulation system is activated in response to vascular injury (1, 7, 11, 12).
Binding of factor VII to tissue factor initiates a cascade of reactions that leads to the formation …

The endothelial cell protein C receptor (EPCR) functions as an important regulator of the
protein C anticoagulant pathway by binding protein C and enhancing activation by the …

Protein C is an important regulatory mechanism of blood coagulation. Protein C functions as
an anticoagulant when converted to the active serine protease form on the endothelial cell …

The endothelial cell protein C receptor (EPCR) is an endothelial cell-specific
transmembrane protein that binds both protein C and activated protein C (APC). EPCR …

Plasma protein C functions as an anticoagulant when it is converted to the active form of
serine protease. Protein C activation has been found to be mediated by the endothelial cell …

The protein C anticoagulant pathway converts the coagulation signal generated by thrombin
into an anticoagulant response through the activation of protein C by the thrombin …

The protein C pathway plays a critical role in the negative regulation of the blood clotting
process. We recently identified an endothelial cell receptor for protein C/activated protein C …

A soluble form of the endothelial cell protein C receptor (EPCR) was analyzed for the ability
to modulate the functional properties of protein C and activated protein C (APC). In a plasma …

The anticoagulant protein C system regulates the activity of coagulation factors VIIIa and Va,
cofactors in the activation of factor X and prothrombin, respectively. Protein C is activated on …