Papillary thyroid carcinoma behavior: clues in the tumor microenvironment
K Bergdorf, DC Ferguson, M Mehrad… - Endocrine-Related …, 2019 - erc.bioscientifica.com
The prevalence of thyroid carcinoma is increasing and represents the most common
endocrine malignancy, with papillary thyroid carcinoma (PTC) being the most frequent …
endocrine malignancy, with papillary thyroid carcinoma (PTC) being the most frequent …
[HTML][HTML] Immune landscape of papillary thyroid cancer and immunotherapeutic implications
KJ Na, H Choi - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Although papillary thyroid cancer (PTC) is curable with excellent survival rate, patients with
dedifferentiated PTC suffer the recurrence or death. As cancer immune escape plays a …
dedifferentiated PTC suffer the recurrence or death. As cancer immune escape plays a …
[HTML][HTML] Immune cell confrontation in the papillary thyroid carcinoma microenvironment
Z Xie, X Li, Y He, S Wu, S Wang, J Sun, Y He… - Frontiers in …, 2020 - frontiersin.org
Background Papillary thyroid cancer has been associated with chronic inflammation. A
systematic understanding of immune cell infiltration in PTC is essential for subsequent …
systematic understanding of immune cell infiltration in PTC is essential for subsequent …
[HTML][HTML] Single‐cell transcriptomic landscape reveals the differences in cell differentiation and immune microenvironment of papillary thyroid carcinoma between …
M Peng, G Wei, Y Zhang, H Li, Y Lai, Y Guo, Y Chen… - Cell & bioscience, 2021 - Springer
Background Papillary thyroid carcinoma (PTC) is the main pathological type of thyroid
carcinoma (TC). Gender is a prominent background parameter for patients with PTC. Here …
carcinoma (TC). Gender is a prominent background parameter for patients with PTC. Here …
Tumor immune microenvironment characteristics of papillary thyroid carcinoma are associated with histopathological aggressiveness and BRAF mutation status
C Means, DR Clayburgh, L Maloney, D Sauer… - Head & …, 2019 - Wiley Online Library
Background Papillary thyroid carcinoma (PTC) follows an indolent course; however, up to
30% of patients develop recurrent disease requiring further treatment. Profiling PTC immune …
30% of patients develop recurrent disease requiring further treatment. Profiling PTC immune …
[HTML][HTML] Immune landscape of thyroid cancers: new insights
E Menicali, M Guzzetti, S Morelli, S Moretti… - Frontiers in …, 2021 - frontiersin.org
Immune system plays a key role in cancer prevention as well as in its initiation and
progression. During multistep development of tumors, cells must acquire the capability to …
progression. During multistep development of tumors, cells must acquire the capability to …
Immune profiling of thyroid carcinomas suggests the existence of two major phenotypes: an ATC-like and a PDTC-like
R Giannini, S Moretti, C Ugolini… - The Journal of …, 2019 - academic.oup.com
Objectives The understanding of the mechanisms underlying thyroid cancer immune escape
can lead to the identification of new molecular targets and/or efficacy biomarkers. For this …
can lead to the identification of new molecular targets and/or efficacy biomarkers. For this …
[HTML][HTML] Papillary thyroid carcinoma landscape and its immunological link with hashimoto thyroiditis at single-cell resolution
J Pan, F Ye, C Yu, Q Zhu, J Li, Y Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
The tumor microenvironment heterogeneity of papillary thyroid cancer (PTC) is poorly
characterized. The relationship between PTC and Hashimoto thyroiditis (HT) is also in …
characterized. The relationship between PTC and Hashimoto thyroiditis (HT) is also in …
[HTML][HTML] Translating the immune microenvironment of thyroid cancer into clinical practice
Thyroid cancer is an excellent model for studying tumor immune microenvironment, as it
often shows local signs of an immune response. The tumor immune microenvironment of …
often shows local signs of an immune response. The tumor immune microenvironment of …
[HTML][HTML] Single-cell transcriptome analysis reveals inter-tumor heterogeneity in bilateral papillary thyroid carcinoma
T Wang, J Shi, L Li, X Zhou, H Zhang, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Background The tumor microenvironment (TME) plays a pivotal role in cancer progression in
papillary thyroid carcinoma (PTC), yet the composition and the phenotype of cells within the …
papillary thyroid carcinoma (PTC), yet the composition and the phenotype of cells within the …