[HTML][HTML] Microsatellite instability and hMLH1 and hMSH2 expression analysis in familial and sporadic colorectal cancer
S Salahshor, K Koelble, C Rubio, A Lindblom - Laboratory investigation, 2001 - Elsevier
Immunohistochemical expression analysis of mismatch repair gene products has been
suggested for the prediction of hereditary nonpolyposis colorectal cancer (HNPCC) carrier …
suggested for the prediction of hereditary nonpolyposis colorectal cancer (HNPCC) carrier …
Immunohistochemistry and microsatellite instability testing for selecting MLH1, MSH2 and MSH6 mutation carriers in hereditary non-polyposis colorectal cancer
T Caldés, J Godino, A Sanchez… - Oncology …, 2004 - spandidos-publications.com
Hereditary non-polyposis colorectal cancer (HNPCC) represents 1-3% of all colorectal
cancers. HNPCC is caused by a constitutional defect in a mismatch repair (MMR) gene …
cancers. HNPCC is caused by a constitutional defect in a mismatch repair (MMR) gene …
Screening for defective DNA mismatch repair in stage II and III colorectal cancer patients
SM Chai, N Zeps, AM Shearwood, F Grieu… - Clinical …, 2004 - Elsevier
Background & Aims: Colorectal cancers associated with the hereditary nonpolyposis
colorectal cancer (HNPCC) syndrome usually present in younger patients, show loss of …
colorectal cancer (HNPCC) syndrome usually present in younger patients, show loss of …
Mutations of hMLH1 and hMSH2 in Patients With Suspected Hereditary Nonpolyposis Colorectal Cancer: Correlation With Microsatellite Instability and Abnormalities …
M Scartozzi, F Bianchi, S Rosati, E Galizia… - Journal of clinical …, 2002 - ascopubs.org
PURPOSE: The relationship between germ-line mutations of hMSH2 and hMLH1,
microsatellite instability (MSI), and loss of DNA mismatch repair (MMR) gene expression …
microsatellite instability (MSI), and loss of DNA mismatch repair (MMR) gene expression …
Microsatellite instability analysis and/or immunostaining for the diagnosis of hereditary nonpolyposis colorectal cancer?
B Halvarsson, A Lindblom, E Rambech, K Lagerstedt… - Virchows Archiv, 2004 - Springer
Hereditary nonpolyposis colorectal cancer (HNPCC) represents 2–4% of colorectal cancers
and is caused by a constitutional defect in a mismatch repair (MMR) gene, most commonly …
and is caused by a constitutional defect in a mismatch repair (MMR) gene, most commonly …
Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression
W Dietmaier, S Wallinger, T Bocker, F Kullmann… - Cancer research, 1997 - AACR
Alterations of the length of simple repetitive genomic sequences (microsatellite instability,
MSI) characterize a distinct mechanism of colorectal carcinogenesis. Such MSI has been …
MSI) characterize a distinct mechanism of colorectal carcinogenesis. Such MSI has been …
Methylation of the hMLH1 and hMSH2 promoter in early-onset sporadic colorectal carcinomas with microsatellite instability
HC Kim, CN Kim, CS Yu, SA Roh, JC Kim - International journal of …, 2003 - Springer
Background and aims. Microsatellite instability (MSI) occurring from defects in mismatch
repair has been found to be associated with about 15% of sporadic colorectal carcinomas …
repair has been found to be associated with about 15% of sporadic colorectal carcinomas …
Microsatellite instability—a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: a study in different groups of patients with …
C Lamberti, R Kruse, C Ruelfs, R Caspari, Y Wang… - Gut, 1999 - gut.bmj.com
BACKGROUND Clinical diagnosis of hereditary non-polyposis colorectal cancer (HNPCC)
is based on a typical family history. As molecular genetic testing is predominantly restricted …
is based on a typical family history. As molecular genetic testing is predominantly restricted …
Microsatellite instability as a predictor of a mutation in a DNA mismatch repair gene in familial colorectal cancer
T Liu, S Wahlberg, E Burek, P Lindblom… - Genes …, 2000 - Wiley Online Library
Germline alterations in human DNA mismatch repair genes are associated with hereditary
nonpolyposis colorectal cancer (HNPCC). Mutation analysis of the genes reveals carriers …
nonpolyposis colorectal cancer (HNPCC). Mutation analysis of the genes reveals carriers …
Immunohistochemical detection of the hMLH1 and hMSH2 proteins in hereditary non-polyposis colon cancer and sporadic colon cancer.
P Plevova, A Krepelova, M Papezova, E Sedláková… - Neoplasma, 2004 - europepmc.org
Defects in DNA mismatch repair system are involved in carcinogenesis of sporadic and
inherited human cancers. We assessed the feasibility of using immunohistochemistry to …
inherited human cancers. We assessed the feasibility of using immunohistochemistry to …
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