Vitamin D has received increased attention recently for its pleiotropic actions on many
chronic diseases. The importance of vitamin D on the regulation of cells of the immune …

In the last 5 years there has been renewed interest in the health benefits of vitamin D. A
central feature of this revival has been new information concerning the nonclassical effects …

Vitamin D is well known for its classical hormonal action related to the maintenance of
mineral and skeletal homeostasis. However, the discovery that vitamin D receptor (VDR) is …

Effects of vitamin D on the immune system have been recognized for over 30years and
stemmed in part from analysis of the dysregulated vitamin D metabolism associated with …

In the past, vitamin D was known for its classical, skeletal action as a regulator of calcium
and bone homoeostasis. Currently, vitamin D was found to have a role in numerous …

An immunomodulatory role for vitamin D was first proposed more than 25 years ago, based
on two salient observations. Firstly it was shown that monocytes/macrophages from patients …

Non-classical actions of vitamin D were first suggested over 30 years ago when receptors for
the active form of vitamin D, 1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3), were detected in …

Immunomodulatory actions of vitamin D have been recognised for over a quarter of a
century, but it is only in the last few years that the significance of this to normal human …

Prominent amongst the non-classical effects of vitamin D is its interaction with the immune
system. Although this has been recognized for many years, it is only through recent studies …

The primary function of vitamin D is to regulate calcium homeostasis, which is essential for
bone formation and resorption. Although diet is a source of vitamin D, most foods are …