RND pump inhibition: in-silico and in-vitro study by Eugenol on clinical strain of E. coli and P. aeruginosa
EE Ashtiani, Z Gholizadeh Siahmazgi, M Mirpour… - In Silico …, 2023 - Springer
Abstract Multidrug-resistant (MDR) gram-negative bacteria pose significant challenges to the
public health. Various factors are involved in the development and spread of MDR strains …
public health. Various factors are involved in the development and spread of MDR strains …
Screening of natural products and derivatives for the identification of RND efflux pump inhibitors
Aim and objective: Overexpression of efflux pumps belonging to the Resistance Nodulation
cell Division (RND) family is the most important intrinsic resistance mechanism of …
cell Division (RND) family is the most important intrinsic resistance mechanism of …
[PDF][PDF] Role of a novel terpenoid as efflux inhibitor in targeting the efflux protein (mexa) of multidrug resistant, Pseudomonas aeruginosa
R Jasmine, BN Selvakumar, S Aishwarya - Int J Pharm Sci Res, 2012 - Citeseer
Pseudomonas aeruginosa, is one among the few drug resistant organisms causing Urinary
Tract Infection. Most strains of Pseudomonas aeruginosa are significantly more resistant …
Tract Infection. Most strains of Pseudomonas aeruginosa are significantly more resistant …
Exploring imidazo[4,5-g]quinoline-4,9-dione derivatives as Acinetobacter baumannii efflux pump inhibitor: an in silico approach
P Brindangnanam, K Ashokkumar… - Journal of …, 2023 - Taylor & Francis
Antimicrobial resistance (AMR) is fast becoming a medical crisis affecting the entire global
population. World Health Organization (WHO) statistics show that globally 0.7 million people …
population. World Health Organization (WHO) statistics show that globally 0.7 million people …
[PDF][PDF] Identification of inhibitors for RND efflux pump of Pseudomonas aeruginosa using structurebased pharmacophore modeling approach
V Aparna, N Mohanalakshmi… - … Journal of Pharmacy …, 2014 - researchgate.net
ABSTRACT Objective: Multidrug resistant Pseudomonas aeruginosa possess multiple ways
of resistance with the expression of efflux pump proteins as one of the major mechanisms …
of resistance with the expression of efflux pump proteins as one of the major mechanisms …
In silico screening and in vitro validation of phytocompounds as multidrug efflux pump inhibitor against E. coli
Multiple drug resistance (MDR) in bacteria has increased globally in recent times. This has
reduced the efficacy of antibiotics and increasing the rate of therapeutic failure. Targeting …
reduced the efficacy of antibiotics and increasing the rate of therapeutic failure. Targeting …
Identification of Potential Therapeutics of Mentha Essential Oil Content as Antibacterial MDR Agents against AcrAB-TolC Multidrug Efflux Pump from Escherichia coli …
R Alenazy - Life, 2024 - mdpi.com
Multidrug-resistant bacterial pathogens, such as E. coli, represent a major human health
threat. Due to the critical need to overcome this dilemma, since the drug efflux pump has a …
threat. Due to the critical need to overcome this dilemma, since the drug efflux pump has a …
In silico and Molecular Docking Studies of Black Pepper Phyto-constituents against EmrD Efflux Pump of E. coli.
P Dongre, R Bhambar… - Indian Journal of …, 2022 - search.ebscohost.com
Multidrug resistance (MDR) bacterial infection is the next pandemic waiting behind the
COVID-19 with annual mortality rate 700000 worldwide. Among the MDR bacteria …
COVID-19 with annual mortality rate 700000 worldwide. Among the MDR bacteria …
In Silico Screening and Experimental Validation of Novel MexAB–OprM Efflux Pump Inhibitors of Pseudomonas aeruginosa
S Abdelmalek, M Hajar, L Salah… - Microbial Drug …, 2024 - liebertpub.com
The emergence of multidrug-resistant Pseudomonas aeruginosa possesses a significant
public health concern. Constitutively expressed MexAB–OprM efflux pumps in P. aeruginosa …
public health concern. Constitutively expressed MexAB–OprM efflux pumps in P. aeruginosa …
[HTML][HTML] The effects of berberine and palmatine on efflux pumps inhibition with different gene patterns in Pseudomonas aeruginosa isolated from burn infections
SS Aghayan, HK Mogadam, M Fazli… - Avicenna journal of …, 2017 - ncbi.nlm.nih.gov
Background: Related Multidrug Resistance (MDR) to efflux pumps is a significant problem in
treating infections caused by Pseudomonas aeruginosa (P. aeruginosa). Plant compounds …
treating infections caused by Pseudomonas aeruginosa (P. aeruginosa). Plant compounds …