Can toxicogenomics provide information on the bioreactivity of diesel exhaust particles?
LJ Reynolds, RJ Richards - Toxicology, 2001 - Elsevier
Epidemiologists have linked increased cardio-respiratory hospital admissions, morbidity and
mortality rates and increases in particulate matter with an aerodynamic diameter less than …
mortality rates and increases in particulate matter with an aerodynamic diameter less than …
Microarray analysis of the effect of diesel exhaust particles on in vitro cultured macrophages
GR Verheyen, JM Nuijten, P Van Hummelen… - Toxicology in vitro, 2004 - Elsevier
Diesel exhaust particles (DEP) have been reported to induce or aggravate pulmonary
diseases, including cancer and asthma. Alveolar macrophages are important cellular targets …
diseases, including cancer and asthma. Alveolar macrophages are important cellular targets …
cDNA microarray analysis of rat alveolar epithelial cells following exposure to organic extract of diesel exhaust particles
E Koike, S Hirano, A Furuyama, T Kobayashi - Toxicology and applied …, 2004 - Elsevier
Diesel exhaust particles (DEP) induce pulmonary diseases including asthma and chronic
bronchitis. Comprehensive evaluation is required to know the mechanisms underlying the …
bronchitis. Comprehensive evaluation is required to know the mechanisms underlying the …
Inflammatory and genotoxic effects of diesel particles in vitro and in vivo
M Dybdahl, L Risom, J Bornholdt, H Autrup… - … /Genetic Toxicology and …, 2004 - Elsevier
Recent studies have identified an indirect genotoxicity pathway involving inflammation as
one of the mechanisms underlying the carcinogenic effects of air pollution/diesel exhaust …
one of the mechanisms underlying the carcinogenic effects of air pollution/diesel exhaust …
cDNA microarray analysis of gene expression in rat alveolar macrophages in response to organic extract of diesel exhaust particles
E Koike, S Hirano, N Shimojo… - Toxicological …, 2002 - academic.oup.com
Diesel exhaust particles (DEP) induce pulmonary diseases including asthma and chronic
bronchitis. Comprehensive evaluation is required to know the effects of pollutants including …
bronchitis. Comprehensive evaluation is required to know the effects of pollutants including …
Microarray analysis of gene expression in rat alveolar epithelial cells exposed to fractionated organic extracts of diesel exhaust particles
S Omura, E Koike, T Kobayashi - Toxicology, 2009 - Elsevier
Diesel exhaust particles (DEP) affect health adversely. Our previous studies revealed that
DEP extracts up-regulated expression of genes related to drug metabolism, antioxidant …
DEP extracts up-regulated expression of genes related to drug metabolism, antioxidant …
Inflammation‐Related Effects of Diesel Engine Exhaust Particles: Studies on Lung Cells In Vitro
PE Schwarze, AI Totlandsdal, M Låg… - BioMed research …, 2013 - Wiley Online Library
Diesel exhaust and its particles (DEP) have been under scrutiny for health effects in
humans. In the development of these effects inflammation is regarded as a key process …
humans. In the development of these effects inflammation is regarded as a key process …
Determination of genotoxicity attributed to diesel exhaust particles in normal human embryonic lung cell (Wi-38) line
JW Lee, HJ Lee, YJ Lee, Y Lim, WJ Sim, JH Jang… - Biomolecules, 2021 - mdpi.com
Several epidemiological studies concluded that inhalation of diesel exhaust particles (DEP)
is associated with an increase in the relative risk of lung cancer. In vitro research evaluating …
is associated with an increase in the relative risk of lung cancer. In vitro research evaluating …
Responses of cultured human airways epithelial cells treated with diesel exhaust extracts will vary with the engine load
MC Madden, LA Dailey, JG Stonehuerner… - Journal of Toxicology …, 2003 - Taylor & Francis
Numerous epidemiological studies have associated levels of ambient particles with mortality
and morbidity, including increased asthma symptoms and pul-monary infections (Dockery et …
and morbidity, including increased asthma symptoms and pul-monary infections (Dockery et …
Differential transcriptional regulation of IL-8 expression by human airway epithelial cells exposed to diesel exhaust particles
TL Tal, SO Simmons, R Silbajoris, L Dailey… - Toxicology and applied …, 2010 - Elsevier
Exposure to diesel exhaust particles (DEP) induces inflammatory signaling characterized by
MAP kinase-mediated activation of NFkB and AP-1 in vitro and in bronchial biopsies …
MAP kinase-mediated activation of NFkB and AP-1 in vitro and in bronchial biopsies …