Astaxanthin protects astrocytes against trauma-induced apoptosis through inhibition of NKCC1 expression via the NF-κB signaling pathway
M Zhang, Z Cui, H Cui, Y Wang, C Zhong - BMC neuroscience, 2017 - Springer
Background Astaxanthin (ATX) is a carotenoid pigment with pleiotropic pharmacological
properties that is seen as a possible drug for treating cerebral ischemic injury and …
properties that is seen as a possible drug for treating cerebral ischemic injury and …
Astaxanthin alleviates cerebral edema by modulating NKCC1 and AQP4 expression after traumatic brain injury in mice
M Zhang, Z Cui, H Cui, Y Cao, Y Wang, C Zhong - BMC neuroscience, 2016 - Springer
Background Astaxanthin is a carotenoid pigment that possesses potent antioxidative, anti-
inflammatory, antitumor, and immunomodulatory activities. Previous studies have …
inflammatory, antitumor, and immunomodulatory activities. Previous studies have …
[HTML][HTML] Astaxanthin provides neuroprotection in an experimental model of traumatic brain injury via the Nrf2/HO-1 pathway
F Gao, X Wu, X Mao, F Niu, B Zhang… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Astaxanthin (ATX) is a carotenoid pigment with effective antioxidant, anti-
inflammatory, antitumor and immunomodulatory actions. ATX has been proposed to exert …
inflammatory, antitumor and immunomodulatory actions. ATX has been proposed to exert …
Astaxanthin alleviates early brain injury following subarachnoid hemorrhage in rats: possible involvement of Akt/bad signaling
XS Zhang, X Zhang, Q Wu, W Li, QR Zhang, CX Wang… - Marine drugs, 2014 - mdpi.com
Apoptosis has been proven to play a crucial role in early brain injury pathogenesis and to
represent a target for the treatment of subarachnoid hemorrhage (SAH). Previously, we …
represent a target for the treatment of subarachnoid hemorrhage (SAH). Previously, we …
Astaxanthin ameliorates oxidative stress and neuronal apoptosis via SIRT1/NRF2/Prx2/ASK1/p38 after traumatic brain injury in mice
XS Zhang, Y Lu, W Li, T Tao, L Peng… - British Journal of …, 2021 - Wiley Online Library
Background and Purpose Oxidative stress and neuronal apoptosis play key roles in
traumatic brain injury. We investigated the protective effects of astaxanthin against traumatic …
traumatic brain injury. We investigated the protective effects of astaxanthin against traumatic …
Astaxanthin as a potential neuroprotective agent for neurological diseases
Neurological diseases, which consist of acute injuries and chronic neurodegeneration, are
the leading causes of human death and disability. However, the pathophysiology of these …
the leading causes of human death and disability. However, the pathophysiology of these …
Neuroprotective effect of astaxanthin against glutamate-induced cytotoxicity in HT22 cells: Involvement of the Akt/GSK-3β pathway
X Wen, A Huang, J Hu, Z Zhong, Y Liu, Z Li, X Pan… - Neuroscience, 2015 - Elsevier
Oxidative stress (OS) mediated the pathogenesis of Alzheimer's disease (AD). Astaxanthin
(ATX) has been reported to exert antioxidant activities as well as neuroprotective effects in …
(ATX) has been reported to exert antioxidant activities as well as neuroprotective effects in …
Astaxanthin ameliorates spinal cord edema and astrocyte activation via suppression of HMGB1/TLR4/NF-κB signaling pathway in a rat model of spinal cord injury
F Abbaszadeh, M Jorjani, MT Joghataei… - Naunyn-Schmiedeberg's …, 2023 - Springer
Spinal cord edema is a quick-onset phenomenon with long-term effects. This complication is
associated with inflammatory responses, as well as poor motor function. No effective …
associated with inflammatory responses, as well as poor motor function. No effective …
Astaxanthin offers neuroprotection and reduces neuroinflammation in experimental subarachnoid hemorrhage
XS Zhang, X Zhang, Q Wu, W Li, CX Wang… - Journal of Surgical …, 2014 - Elsevier
Background Neuroinflammation has been proven to play a crucial role in early brain injury
pathogenesis and represents a target for treatment of subarachnoid hemorrhage (SAH) …
pathogenesis and represents a target for treatment of subarachnoid hemorrhage (SAH) …
Astaxanthin mitigates subarachnoid hemorrhage injury primarily by increasing sirtuin 1 and inhibiting the Toll‐like receptor 4 signaling pathway
X Zhang, Y Lu, Q Wu, H Dai, W Li, S Lv… - The FASEB …, 2019 - Wiley Online Library
Inflammation plays a key role in the progression of subarachnoid hemorrhage (SAH). Here,
we examined the effects of astaxanthin (ATX) on the inflammatory response and secondary …
we examined the effects of astaxanthin (ATX) on the inflammatory response and secondary …