The effect of captopril 25 to 50 mg twice daily on 24 h blood pressures was compared with
placebo in 14 patients with essential hypertension. Captopril was started in a dose of 25 mg …

Results In the 31 subjects of the study, the 24-h mean sys-tolic blood pressure obtained
under placebo was п. пно S В Р. nlv-htlv reduced hv. pt pril (133 4 t 2 3 versus 1 2 (!!! mn11 …

Captopril was administered (50 mg orally) to 88 untreated hypertensive patients (70 with
essential hypertension, eight with renal arterial disease, 10 with renal parenchymal disease) …

1. We randomized 475 men whose diastolic blood pressure was 92–109 mmHg to either
placebo-or captopril-treated (37.5, 75 and 150 mg/day) groups for 7 weeks. 2. After 7 weeks …

The usual regimens of captopril-twice or thrice daily administration-are based on the
duration of the decrease in plasma angiotensin II induced by captopril. In a study performed …

1 After a period of 7+/‐1.4 months of good control of hypertension by thrice daily
administration of captopril (85+/‐9 mg three times a day), captopril was given twice daily and …

The hypotensive effect of captopril 50 mg twice daily and of captopril 50 mg+
hydrochlorothiazide (HCTZ) 25 mg once daily was studied in 12 patients with mild to …

The efficacy of a once‐daily dose of enalapril was compared with a thrice‐daily dose of
captopril in an open‐label, randomized parallel group study of 27 hypertensive patients. The …

An investigation of the therapeutic effect of a once daily dose of captopril was carried out on
19 patients with essential hypertension. Captopril was administered at a dose of 50 mg/day …

After a 4-to 6-week placebo lead-in period, 382 mild-to-moderate hypertensive patients with
diastolic blood pressures remaining between 92 and 109 mmHg were randomized to double …