Abstract Captopril (12.5–25 mg bd) was compared with placebo in a double-blind, cross-
over study in elderly, hypertensive subjects. Sixteen patients, aged between 65 and 80 …

The extent and duration of the antihypertensive effect of enalapril and captopril, both given
once daily, were evaluated in 12 mild-to-moderate essential hypertensives by 24-hour …

• We randomized 495 men with uncomplicated hypertension (diastolic BP, 92 to 109 mm Hg)
to one of five captopril regimens at the following dosages: 12.5 mg three times a day, 25 mg …

A controlled study was conducted in hypertensive patients to investigate whether captopril
can be substituted for the various other antihypertensive drugs (not including diuretics) to …

In 12 essential hypertensive patients insufficiently controlled by treatment with 50 mg
hydrochlorothiazide, the blood pressure lowering effect of the addition of 25 mg captopril …

• The effect of low doses (25 mg three times a day) of captopril was evaluated in 16 patients
with mild to moderate essential hypertension, previously uncontrolled by …

We studied the effectiveness of 50 mg captopril in reducing blood pressure in 27 elderly
hypertensive patients. Comparison with a placebo group has shown a significant difference …

1 The effect of captopril on autonomic reflex functions has been investigated in fifteen
patients with essential hypertension by examining their responses to tests of baroreceptor …

The blood pressure response to the first dose of captopril (6.25 mg, 12.5 mg, or 25 mg) was
measured in 65 treated, severely hypertensive patients. Mean supine blood pressure was …

Thirty patients (21 F, 9 M) of mean age 55.3 years with non-insulin dependent diabetes
mellitus of mean duration 10.8 years and hypertension (blood pressure 160/95 mm Hg) of …