Synthesis and properties of oligonucleotides containing aminodeoxythymidine units

SM Gryaznov, RL Letsinger - Nucleic acids research, 1992 - academic.oup.com
Procedures are described for synthesis via solid support methodology of oligonucleotide
analogues derived in part from 3′-amino-3′-deoxythymidine or 5′-amino-5 …

The application of oligodeoxyribonucleotides containing degenerate bases

DM Brown, P Kong Thoo Lin - Collection of Czechoslovak …, 1990 - cccc.uochb.cas.cz
ABSTRACf Oligodeoxyribonuc1eotides (17-mers) containing one to three residues of the
bases N4-methoxycytosine (M) or the bicyclic 61l. 8H-dihydropyrimido [4, 5-c][1, 2] oxazin-7 …

Oligonucleotides derived from 5-(1-propynyl)-2′-O-allyl-uridine and 5-(1-propynyl)-2′-O-allyl-cytidine: synthesis and RNA duplex formation

BC Froehler, RJ Jones, X Cao, TJ Terhorst - Tetrahedron letters, 1993 - Elsevier
Oligonucleotides Derived from 5-( l-Propynyl)-2’~0-Allyl- Uridine and 51(l-Propgnyl)-2’~&AIlyl-Cytidine:
Synthesis and R Page 1 Teu&edmn Letters. Vol. 34. No. 6. pp. 1003-1006.1993 0040-4039)93 …

9‐(2′‐Deoxy‐β‐D‐xylofuranosyl)adenine Building Blocks for Solid‐Phase Synthesis and Properties of Oligo(2′‐deoxy‐xylonucleotides)

H Roscmeycr, M Krečmerova, F Seela - Helvetica chimica acta, 1991 - Wiley Online Library
Abstract The 9‐(2′‐deoxy‐à‐d‐threo‐pentofuranosyl) adenine (= 9‐(2′‐deoxy‐à‐d‐
xylofuranosyl) adeninc, xAd; 2) was protected at its 6‐NH2 group with cither a benzoyl (5a) …

Synthesis and Evaluation of Oligodeoxynucleotides Containing 3′-O-Ethyl-4′-C-(hydroxymethyl)thymidine: Introduction of a Novel Class of Phosphodiester …

LH Dreio⊘ e, J Wengel - Nucleosides, Nucleotides & Nucleic Acids, 1994 - Taylor & Francis
O-Ethyl-4′-C-(hydroxymethyl) thymidine (5) was synthesized and converted into the
phosphoramidite building block 8. Novel oligodeoxynucleotide analogues containing 4′-C …

Improved synthesis of oligonucleotides with an allylic backbone. Oligonucleotides containing acyclic, achiral nucleoside analogues: N-1 or N-9-[3-hydroxy-2 …

BM Dahl, U Henriksen, O Dahl - Organic & Biomolecular Chemistry, 2006 - pubs.rsc.org
An improved phosphoramidite method is described to prepare oligonucleotides modified
with the acyclic, achiral monomers 1. Examination of dimers, prepared on solid support or in …

Novel 2′-deoxycytidine analogues as pH independent substitutes of protonated cytosines in triple helix forming oligonucleotides

E Bédu, R Benhida, M Devys, JL Fourrey - Tetrahedron letters, 1999 - Elsevier
The N-acetyl derivatives 1a and 2a of the aminotriazole and aminoimidazole 2′-
deoxynucleosides 1 and 2 were synthesized as potential substitutes of protonated 2 …

1-(2-Deoxy-α-and β-D-erythro-pentofuranosyl)-2-(thymin-1-yl) ethane derivatives as conformational probes for altDNA oligonucleotides

CL Scremin, JH Boal, A Wilk, LR Phillips, L Zhou… - Tetrahedron letters, 1995 - Elsevier
The novel deoxyribonucleoside analogues 1a, b have been synthesized in a straightforward
manner from 2-deoxy-D-ribose. These modified nucleosides have also been converted to …

Oligonucleotides with (N-thymin-1-ylacetyl) 1-phenylserinol in backbone: Chiral acyclic analogues that form dna triplexes

VS Rana, VA Kumar, KN Ganesh - Bioorganic & Medicinal Chemistry …, 1997 - Elsevier
The synthesis of oligonucleotides containing chiral acyclic 2 (R/S)-(N-thymin-1-ylacetyl)-
amino-1 (R/S)-phenyl-1, 3-propanediol unit in the backbone (l, R Ar) is described. When …

Conformationally locked nucleosides. Synthesis and hybridization properties of oligodeoxynucleotides containing 2′, 4′-C-bridged 2′-deoxynucleosides

G Wang, E Gunic, JL Girardet, V Stoisavljevic - Bioorganic & medicinal …, 1999 - Elsevier
A conformationally locked, 2′, 4′-C-bridged 2′-deoxyribofuranoside2 was condensed
with silylated pyrimidines to give 2′, 4′-C-bridged bicyclonucleosides, which were …