This article describes the detailed synthetic protocol for the preparation of oligonucleotides
containing 2‐guanidinoethyl‐2′‐deoxynebularine and 2‐ureidoethyl‐2 …

The method for scaled-up production of α-l-LNA phosphoramidite building blocks containing
thymine and 5-methylcytosine nucleobases is described. Binding properties of pyrimidine …

Abstract Derivatives of 2'‐O‐4'‐C‐Ethylene‐bridged Nucleic Acid (ENA) monomer, a
nucleoside used in the preparation of antisense modified oligonucleotides and featuring an …

Abstract 3′, 4′-Ethyleneoxy-bridged 5-methyluridine derivatives with methyl groups in the
bridge,(R)-Me-3′, 4′-EoNA-T and (S)-Me-3′, 4′-EoNA-T, were synthesized, and these …

The synthesis of oligonucleotides containing 7‐(2‐deoxy‐β‐D‐erythro‐pentofuranosyl)
guanine and 8‐amino‐2′‐deoxyguanosine was accomplished. The viable intermediate N2 …

Abstract A series of 1-(3-alkyl-2, 3-dideoxy-α, β-d-erythro-pentofuranosyl) thymines (3′-
alkyl-3′-deoxythymidines) has been prepared from 5-O-(tert-butyldiphenylsilyl)-2, 3 …

It will be demonstrated that 5′-O-DMT-N-acyl-deoxyribonucleosides, 5′-O-Lev-2′-O-
MTHP-N-acyl-ribonucleosidea and, also, 2′-O-MTHP-N-acyl-ara-cyti-dine can be coupled …

Multiple incorporations of 7-chloro-7-deaza-2′-deoxyguanosine in place of 2′-
deoxyguanosine have been performed into a triple helix-forming oligodeoxyribonucleotide …

To construct the nuclease-resistant oligodeoxynucleotides (ODNs) with natural
phosphodiester linkages, we synthesized ODNs that contain 6 'α-[N-(aminoalkyl) …

Fully modified oligonucleotides were synthesised from the 3-O-phosphoramidites of
monomethoxytritylated trans-3-hydroxy-N-[(N6-benzoyladenin-9-yl)-acetyl]-prolinol [(2S, 3R) …