Straightforward Synthesis of Non‐Natural Selenium Containing Amino Acid Derivatives and Peptides
A series of non‐natural selenium‐containing amino acid derivatives and peptides have
been synthesized, in a flexible and modular strategy. The peptide coupling reaction between …
been synthesized, in a flexible and modular strategy. The peptide coupling reaction between …
Efficient Synthesis of Modular Amino Acid Derivatives Containing Selenium with Pronounced GPx‐Like Activity
EE Alberto, LC Soares, JH Sudati, ACA Borges… - 2009 - Wiley Online Library
New chiral selenide‐and diselenide amino acid derivatives have been synthesized. By a
simple and efficient two‐step route, these new compounds were obtained from inexpensive …
simple and efficient two‐step route, these new compounds were obtained from inexpensive …
Novel selenium-containing non-natural diamino acids
R Caputo, S Capone, M Della Greca, L Longobardo… - Tetrahedron letters, 2007 - Elsevier
The general synthesis of a new class of non-natural diamino acids, 2-amino-3-[(2′-
aminoalkyl) seleno] propanoic acids, or Se-(aminoalkyl) selenocysteines, is reported. Under …
aminoalkyl) seleno] propanoic acids, or Se-(aminoalkyl) selenocysteines, is reported. Under …
Selenocysteine derivatives for chemoselective ligations
MD Gieselman, Y Zhu, H Zhou, D Galonic… - …, 2002 - experts.illinois.edu
Selenium variation on a cysteine theme: Selenocysteine (Sec) has been employed in a
number of chemoselective ligations. Sec can be used for native chemical and expressed …
number of chemoselective ligations. Sec can be used for native chemical and expressed …
Synthesis of Selenocysteine and Selenomethionine Derivatives from Sulfur‐Containing Amino Acids
M Iwaoka, R Ooka, T Nakazato… - Chemistry & …, 2008 - Wiley Online Library
Selenium‐containing amino acids have attracted increasing interest from view points of the
importance as active centers of several selenoenzymes, the biological synthesis, the …
importance as active centers of several selenoenzymes, the biological synthesis, the …
Synthesis and utility of β-selenol-phenylalanine for native chemical ligation–deselenization chemistry
An efficient synthetic route to a suitably protected β-selenol-phenylalanine derivative from
commercially available Garner's aldehyde is described. The incorporation of this building …
commercially available Garner's aldehyde is described. The incorporation of this building …
[HTML][HTML] Selenium in peptide chemistry
Ö Pehlivan, M Waliczek, M Kijewska, P Stefanowicz - Molecules, 2023 - mdpi.com
In recent years, researchers have been exploring the potential of incorporating selenium into
peptides, as this element possesses unique properties that can enhance the reactivity of …
peptides, as this element possesses unique properties that can enhance the reactivity of …
Isoselenocyanates derived from amino acid esters: An expedient synthesis and application to the assembly of selenoureidopeptidomimetics, unsymmetrical …
HP Hemantha, VV Sureshbabu - Journal of Peptide Science, 2010 - Wiley Online Library
An important class of organoselenium compounds‐α‐isoselenocyanato esters 4 hasbeen
prepared by a reaction of α‐isocyano esters with elemental selenium powder. The reaction …
prepared by a reaction of α‐isocyano esters with elemental selenium powder. The reaction …
Straightforward method for the synthesis of selenocysteine and selenocystine derivatives from l-serine methyl ester
A set of selenoamino acids has been efficiently synthesized under smooth conditions by a
simple, flexible and modular strategy. In this method, O-mesylated l-serine methyl ester is …
simple, flexible and modular strategy. In this method, O-mesylated l-serine methyl ester is …
Synthesis of selenopeptides: an alternative way of incorporating selenocystine
S Aravindhan, HB Singh, M Zeller, RJ Butcher - Amino acids, 2019 - Springer
Selenocysteine (Sec) residue cannot be directly attached to a peptide sequence unless the
selenol form is protected beforehand and several problems have been reported in the …
selenol form is protected beforehand and several problems have been reported in the …