Reward-associated inhibition and pain-associated excitation lasting seconds in single intralaminar thalamic units

JJ Keene - Brain Research, 1973 - Elsevier
Reward sites in the medial forebrain bundle (MFB) and aversive reticular sites (RET) send
projections to the medial thalamus and elicit opposite changes in intralaminar unit activity …

Dissociated mesencephalic responses to medial and ventral thalamic nuclei stimulation in rats: Relationship to analgesic mechanisms

S Sakata, F Shima, M Kato, M Fukui - Journal of neurosurgery, 1989 - thejns.org
✓ To investigate the mechanism of analgesia noted with electrical stimulation of the thalamic
sensory relay nucleus and medial thalamus, modulations of neuronal activities in the …

Intrathecal coadministration of serotonin and morphine differentially modulates the tail-flick reflex of intact and spinal rats

C Advokat - Pharmacology Biochemistry and Behavior, 1993 - Elsevier
In a previous study, we found that the antinociceptive effect of IT-administered morphine on
the tail-flick (TF) reflex of rats was potentiated within 1 day after spinal transection. This …

Response patterns of cells in the feline caudal nucleus reticularis gigantocellularis after noxious trigeminal and spinal stimulation

GS Pearl, KV Anderson - Experimental Neurology, 1978 - Elsevier
Nucleus reticularis gigantocellularis has been shown, using both behavioral and
physiological techniques, to be involved in the processing of nociceptive information in …

Functional and ultrastructural neuroanatomy of interactive intratectal/tectonigral mesencephalic opioid inhibitory links and nigrotectal GABAergic pathways …

SJ Ribeiro, JG Ciscato Jr, R De Oliveira… - Journal of Chemical …, 2005 - Elsevier
In the present study, the functional neuroanatomy of nigrotectal–tectonigral pathways as well
as the effects of central administration of opioid antagonists on aversive stimuli-induced …

[HTML][HTML] Neurotoxic lesions of the pedunculopontine tegmental nucleus impair the elaboration of postictal antinociception

RC de Oliveira, R de Oliveira, LL Falconi-Sobrinho… - Physiology & …, 2018 - Elsevier
Generalised tonic-clonic seizures, generated by abnormal neuronal hyper-activity, cause a
significant and long-lasting increase in the nociceptive threshold. The pedunculopontine …

The anterior pretectal nucleus participates as a relay station in the glutamate-, but not morphine-induced antinociception from the dorsal raphe nucleus in rats

WA Prado, FA Faganello - Pain, 2000 - Elsevier
The anterior pretectal nucleus (APtN) and the dorsal raphe nucleus (DRN) are involved in
descending pathways that control noxious inputs to the spinal cord and participate in the …

Opiate-like substances mediate norepinephrine-induced but not serotonin-induced antinociception at spinal level Reevaluation by an electrophysiological model of …

J Ma, J Qiao, N Dafny - Life Sciences, 2001 - Elsevier
After subcutaneous injection of formalin (5%, 50 μl) into a hindpaw of rats, biphasic
excitatory nociceptive discharges were recorded extracellularly in thalamic parafascicular …

The role of dorsomedial and ventrolateral columns of the periaqueductal gray matter and in situ 5‐HT2A and 5‐HT2C serotonergic receptors in post‐ictal …

RL de Freitas, RC de Oliveira, R de Oliveira… - Synapse, 2014 - Wiley Online Library
The periaqueductal gray matter (PAG) consists in a brainstem structure rich in 5‐
hydroxytryptamine (5‐HT) inputs related to the modulation of pain. The involvement of each …

The antinociceptive role of a bulbospinal serotonergic pathway in the rat brain

MY Liu, CF Su, MT Lin - Pain, 1988 - Elsevier
The antinociceptive role of spinal serotonin (5-HT) neurons descending from 5-HT cells near
the ventrolateral surface of the medulla oblongata was investigated by stimulating these …