5-Hydroxytryptamine 1A receptors in the dorsomedial hypothalamus connected to dorsal raphe nucleus inputs modulate defensive behaviours and mediate innate …

AF Biagioni, RC de Oliveira, R de Oliveira… - European …, 2016 - Elsevier
The dorsal raphe nucleus (DRN) is an important brainstem source of 5-hydroxytryptamine (5-
HT), and 5-HT plays a key role in the regulation of panic attacks. The aim of the present …

Intrinsic connections within the pedunculopontine tegmental nucleus are critical to the elaboration of post‐ictal antinociception

EC Mazzei‐Silva, RC de Oliveira, TDA Garcia… - Synapse, 2014 - Wiley Online Library
This study investigated the intrinsic connections of a key‐structure of the endogenous pain
inhibitory system, the pedunculopontine tegmental nucleus (PPTN), in post‐ictal …

An ascending serotonergic pain modulation pathway from the dorsal raphe nucleus to the parafascicularis nucleus of the thalamus

E Andersen, N Dafny - Brain Research, 1983 - Elsevier
Three types of spontaneously active neurons were found in the parafascicularis (PF)
nucleus of the thalamus of the rat: slow firing units (0.5–10 spikes/s), bursting units (2–5 …

Antagonization of clonidine-and morphine-promoted antinociception by kainic acid lesion of nucleus reticularis gigantocellularis in the rat

YY Lai, SHH Chan - Experimental Neurology, 1982 - Elsevier
We evaluated the participation of nucleus reticularis gigantocellularis (NRGC) in clonidine-
and morphine-induced analgesia in young rats, using the hot-plate assay as the nociceptive …

Response of neurons in the thalamic nucleus submedius (Sm) to noxious stimulation and electrophysiological identification of on-and off-cells in rats

JJ Fu, JS Tang, B Yuan, H Jia - Pain, 2002 - Elsevier
Previous studies have indicated that thalamic nucleus submedius (Sm) is involved in
nociceptive modulation and plays an important role in an endogenous analgesic system (a …

Chronic Fluoxetine Impairs the Effects of 5-HT1A and 5-HT2C Receptors Activation in the PAG and Amygdala on Antinociception Induced by Aversive Situation in …

D Baptista-de-Souza, LRR Tavares… - Frontiers in …, 2020 - frontiersin.org
Growing evidence suggests an important role of fluoxetine with serotonin 5-HT1A and 5-
HT2C receptors in the modulation of emotion and nociception in brain areas such as the …

Serotonin neuronal release from dorsal hippocampus following electrical stimulation of the dorsal and median raphe nuclei in conscious rats

DJ Mokler, D Lariviere, DW Johnson… - …, 1998 - Wiley Online Library
Abstract We have studied 5‐hydroxytryptamine (5‐HT) release in the hippocampal formation
following electrical stimulation of the dorsal and median raphé nuclei in the behaving rat …

Effects of thalamic parafascicular stimulation on the periaqueductal gray and adjacent reticular formation neurons. A possible contribution to pain control mechanisms

S Sakata, F Shima, M Kato, M Fukui - Brain research, 1988 - Elsevier
To investigate the mechanism of analgesic effect of electrical stimulation of the thalamic
parafascicular nucleus (Pf), we studied modulations of neuronal activities in the …

Descending antinociception induced by secondary somatosensory cortex stimulation in experimental neuropathy: role of the medullospinal serotonergic pathway

B Sagalajev, H Viisanen, H Wei… - Journal of …, 2017 - journals.physiology.org
Stimulation of the secondary somatosensory cortex (S2) has attenuated pain in humans and
inflammatory nociception in animals. Here we studied S2 stimulation-induced …

The antinociceptive effect of 17β-estradiol in the nucleus paragigantocellularis lateralis of male rats may be mediated by the NMDA receptors

R Khakpay, M Azaddar, F Khakpay - Physiology and Pharmacology, 2016 - ppj.phypha.ir
Introduction: The nucleus paragigantocellularis lateralis (LPGi) is involved in the descending
pain modulation. The neurostreoid, 17β-estradiol found in the PGi nucleus and modulates …