Object Therapies that use bioactive materials as replacement extracellular matrices may
hold the potential to mitigate the inhibition of regeneration observed after central nervous …

OBJECTIVE Spinal cord injury occurs in 2 phases. The initial trauma is followed by
inflammation that leads to fibrous scar tissue, glial scarring, and cavity formation. Scarring …

Hydrogel scaffolds which bridge the lesion, together with stem cell therapy represent a
promising approach for spinal cord injury (SCI) repair. In this study, a hydroxyphenyl …

Object. Spinal cord injury (SCI) is a complex pathological entity, the treatment of which
requires a multipronged approach. One way to integrate different therapeutic strategies for …

A major hurdle for regeneration after spinal cord injury (SCI) is the ability of axons to
penetrate and grow through the scar tissue. After SCI, inflammatory cells, astrocytes and …

Traumatic spinal cord injury (SCI) causes damage and degeneration at and around the
lesion site resulting in a loss of function. SCI presents a complex regenerative problem due …

Numerous biomaterials based on extracellular matrix-components have been developed. It
was our aim to investigate whether a hyaluronic acid–based hydrogel improves neuronal …

Recovery from traumatic spinal cord injury (SCI) usually fails due to a cascade of cellular
and molecular events that compromise neural tissue reconstitution by giving rise to glial …

Self-healing natural hydrogels still suffer from some issues such as unfit stiffness, poor
healing efficiency, and lack of biocompatibility and hydrolytic stability, although they have …

Object Hydrogels are nontoxic, chemically inert synthetic polymers with a high water content
and large surface area that provide mechanical support for cells and axons when implanted …