J. Neurochem.(2008) 104, 1565–1576. Abstract Chondroitin sulfate (CS) is a major
microenvironmental molecule in the CNS, and there have been few reports about its …

Protective effects of chondroitin sulfate proteoglycans (CSPGs) from rat's brain against
delayed cell death induced by excitatory amino acids were examined in cultured neurons of …

The role of chondroitin sulfate proteoglycans (CSPGs) on excitotoxic cell death and long-
term survival of neurons were investigated in primary cultured neurons of the rat cortex …

Growing numbers of studies indicate that polysaccharides influence signaling events
important for brain function. It has been speculated that such polysaccharide modulation of …

Excess extracellular glutamate leads to excitotoxicity, which induces neuronal death through
the overactivation of N-methyl-D-aspartate receptors (NMDARs). Excitotoxicity is thought to …

We have previously reported that a sulfur-containing neuroprotective substance named
serofendic acid was purified and isolated from lipophilic extract of fetal calf serum (FCS). In …

Chitooligosaccharides (COSs), the biodegradation product of chitosan, have demonstrated
a diverse array of biological activities. Here we report the protective effect of COSs (MW 800) …

We have previously reported that a novel neuroprotective substance named serofendic acid
was purified and isolated from ether extract of fetal calf serum. In the present study, we …

Glutamate (10− 7m) and one of its non-NMDA receptor agonists, kainic acid (10− 4m), were
administered to rat cerebellar granular cell cultures, and the neuroprotective role of salicylic …

The rat hippocampal slice preparation and its electrophysiology were used to assess the
toxicity of two sulfur-containing amino acids, l-cysteate (CA) and l-cysteine (CYS). Both …