Morphologic changes in the lung during the lifespan of Fischer 344 rats

KE Pinkerton, BE Barry, JJ O'Neil… - American Journal of …, 1982 - Wiley Online Library
Pulmonary structure and function were quantitatively investigated over the lifespan of the
Fischer 344 rat by morphometric and physiologic techniques. Male animals 1 week, 6 …

Invited Review: pulmonary alveoli: formation, the “call for oxygen,” and other regulators

D Massaro, GD Massaro - American Journal of Physiology …, 2002 - journals.physiology.org
The lung's only known essential function is to provide sufficient alveolar surface to meet the
organism's need for oxygen and elimination of CO2. The importance of the magnitude of …

Mechanisms that determine functional residual capacity in different mammalian species

JR Gillespie - American Review of Respiratory Disease, 1983 - atsjournals.org
Introduction (characteristics of the chest wall may be a predominant factor in mammalian
respiratory mechanics. Of particular interest is the relative stiffness and inherent relaxed …

Estimation of cell numbers and volumes of bronchiolar epithelium during rabbit lung maturation

DM Hyde, CG Plopper, PH Kass… - American Journal of …, 1983 - Wiley Online Library
To estimate the numbers and volumes of bronchiolar epithelial cells during lung maturation,
we examined rabbits at three time points, 30 days gestation and 4 and 17 weeks postnatal …

Assessment of air space size characteristics by intercept (chord) measurement: an accurate and efficient stereological approach

L Knudsen, ER Weibel… - Journal of applied …, 2010 - journals.physiology.org
The mean linear intercept (chord) length (L m) is a useful parameter of peripheral lung
structure as it describes the mean free distance in the air spaces. It is often misinterpreted as …

Relationships between alveolar size and fibre distribution in a mammalian lung alveolar duct model

E Denny, RC Schroter - 1997 - asmedigitalcollection.asme.org
A finite element model, comprising an assemblage of tetrakaidecahedra or truncated
octahedra, is used to represent an alveolar duct unit. The dimensions of the elastin and …

Retinoic acid receptor-α regulates pulmonary alveolus formation in mice after, but not during, perinatal period

G De Carlo Massaro, D Massaro… - American Journal of …, 2003 - journals.physiology.org
The formation of pulmonary alveoli in mice and rats by subdivision of alveolar saccules that
constitute the newborn's gas-exchange region ends by approximately postnatal day 14 …

Changes in alveolar epithelial cell proportions during fetal and postnatal development in sheep

SJ Flecknoe, MJ Wallace, ML Cock… - … of Physiology-Lung …, 2003 - journals.physiology.org
Basal lung expansion is an important determinant of alveolar epithelial cell (AEC)
phenotype in the fetus. Because basal lung expansion increases toward term and is …

Factors related to the appearance of alveolar macrophages in the developing lung

RF Jacobs, CB Wilson, S Palmer… - American Review of …, 1985 - atsjournals.org
The numbers of alveolar macrophages (AM) are known to be low in utero and to increase
rapidly after birth. This study analyzed factors related to the appearance of AM in the lungs of …

Fetal rhesus monkey lung development: lobar differences and discordances between stability and distensibility

RV Kotas, PM Farrell, RE Ulane… - Journal of Applied …, 1977 - journals.physiology.org
Fetal rhesus monkey lung development: lobar differences and discordances between stability
and distensibility Page 1 Fetal rhesus monkey lung development: lobar differences and discor …