Research efforts to combat antimalarial drug resistance rely on quick, robust, and sensitive
methods to genetically characterize Plasmodium falciparum parasites. We developed a …

Background Single nucleotide polymorphism (SNP) genotyping provides the means to
develop a practical, rapid, inexpensive assay that will uniquely identify any Plasmodium …

The diversity in the Plasmodium falciparum genome can be used to explore parasite
population dynamics, with practical applications to malaria control. The ability to identify the …

Genetic polymorphisms in P. falciparum can be used to indicate the parasite's susceptibility
to antimalarial drugs as well as its geographical origin. Both of these factors are key to …

The evolution of genetic mechanisms for host immune evasion and anti-malarial resistance
has enabled the Plasmodium falciparum malaria parasite to inflict high morbidity and …

Background Analysis of single nucleotide polymorphisms (SNPs) derived from whole-
genome studies allows for rapid evaluation of genome-wide diversity, and genomic …

Whole-genome methods are changing the scope of biological questions that can be
addressed in malaria research. In the rich context provided by Plasmodium falciparum …

Molecular surveillance for drug-resistant malaria parasites requires reliable, timely, and
scalable methods. These data may be efficiently produced by genotyping parasite …

Background: Antimalarial drug resistance is a major obstacle to sustainable malaria control.
Here we use amplicon sequencing to describe molecular markers of drug resistance in …

Plasmodium falciparum malaria cases in Africa represent over 90% of the global burden
with Mali being amongst the 11 highest burden countries that account for 70% of this annual …