Background Although several transcriptome-wide association studies (TWASs) have been
performed to identify genes associated with overall breast cancer (BC) risk, only a few TWAS …

Previous transcriptome‐wide association studies (TWAS) have identified breast cancer risk
genes by integrating data from expression quantitative loci and genome‐wide association …

Genome-wide association studies (GWAS) have identified more than 200 genomic loci for
breast cancer risk, but specific causal genes in most of these loci have not been identified. In …

Splicing-based transcriptome-wide association studies (splicing-TWASs) of breast cancer
have the potential to identify new susceptibility genes. However, existing splicing-TWASs …

Genome-wide association studies (GWASs) have identified more than 200 genomic loci for
breast cancer risk, but specific causal genes in most of these loci have not been identified. In …

Background Directly comparing gene expression profiles of estrogen receptor-positive
(ER+) and estrogen receptor-negative (ER−) breast cancers cannot determine whether …

Introduction Breast cancer is a heterogeneous disease and may be characterized on the
basis of whether estrogen receptors (ER) are expressed in the tumour cells. ER status of …

Background Although genome-wide association studies (GWAS) of breast cancer (BC)
identified common variants which differ between intrinsic subtypes, genes through which …

Genome-wide association studies (GWASs) have identified more than 150 common genetic
loci for breast cancer risk. However, the target genes and underlying mechanisms remain …

Estrogen signaling plays an essential role in breast cancer progression, and estrogen
receptor (ER) status has long been a marker of hormone responsiveness. However, ER …