Ligustrazine attenuates myocardial injury induced by coronary microembolization in rats by activating the PI3K/Akt pathway
Q Su, X Lv, Z Ye - Oxidative Medicine and Cellular Longevity, 2019 - Wiley Online Library
Background/Aims. Coronary microembolization‐(CME‐) induced myocardial injury and
progressive cardiac dysfunction are mainly caused due to CME‐induced myocardial local …
progressive cardiac dysfunction are mainly caused due to CME‐induced myocardial local …
Breviscapine pretreatment inhibits myocardial inflammation and apoptosis in rats after coronary microembolization by activating the PI3K/Akt/GSK-3β signaling …
ZQ Chen, Y Zhou, F Chen, JW Huang… - Drug design …, 2021 - Taylor & Francis
Purpose Coronary microembolization (CME) can cause myocardial inflammation, apoptosis
and progressive cardiac dysfunction. On the other hand, breviscapine exerts a significant …
and progressive cardiac dysfunction. On the other hand, breviscapine exerts a significant …
[HTML][HTML] Effects of nicorandil on PI3K/Akt signaling pathway and its anti-apoptotic mechanisms in coronary microembolization in rats
Q Su, L Li, J Zhao, Y Sun, H Yang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Coronary microembolization (CME) is a common complication of percutaneous coronary
intervention (PCI) for acute coronary syndrome. It leads to myocardial apoptosis and cardiac …
intervention (PCI) for acute coronary syndrome. It leads to myocardial apoptosis and cardiac …
Resveratrol pretreatment inhibits myocardial apoptosis in rats following coronary microembolization via inducing the PI3K/Akt/GSK-3β signaling cascade
T Li, Z Chen, Y Zhou, H Li, J Xie, L Li - Drug Design, Development …, 2021 - Taylor & Francis
Purpose Coronary microembolization (CME) is associated with progressive cardiac
dysfunction, myocardial inflammation, and apoptosis. Resveratrol (RES) has a considerable …
dysfunction, myocardial inflammation, and apoptosis. Resveratrol (RES) has a considerable …
Nobiletin protects against myocardial injury and myocardial apoptosis following coronary microembolization via activating PI3K/Akt pathway in rats
Q Mao, X Liang, Y Wu, Y Lu - Naunyn-Schmiedeberg's Archives of …, 2019 - Springer
It has been found that use of drugs which upregulate the PI3K/Akt pathway can effectively
reduce cardiomyocyte apoptosis which has been induced by coronary microembolization …
reduce cardiomyocyte apoptosis which has been induced by coronary microembolization …
Ligustrazine attenuates myocardial ischemia reperfusion injury in rats by activating the phosphatidylinositol 3-kinase/Akt pathway
L Lv, Q Meng, J Xu, J Gong, Y Cheng… - Annals of Clinical & …, 2012 - Assoc Clin Scientists
Materials and Methods Sprague-Dawley rats (n= 68, weighing 250–280g) were divided into
sham (n= 8), IR control (n= 10), 3 TMP pretreated (5, 10, 30mg/kg, n= 10, respectively) …
sham (n= 8), IR control (n= 10), 3 TMP pretreated (5, 10, 30mg/kg, n= 10, respectively) …
[HTML][HTML] Puerarin pretreatment attenuates cardiomyocyte apoptosis induced by coronary microembolization in rats by activating the PI3K/Akt/GSK-3β signaling …
ZQ Chen, Y Zhou, JW Huang, F Chen… - Korean J Physiol …, 2021 - synapse.koreamed.org
Coronary microembolization (CME) is associated with cardiomyocyte apoptosis and cardiac
dysfunction. Puerarin confers protection against multiple cardiovascular diseases, but its …
dysfunction. Puerarin confers protection against multiple cardiovascular diseases, but its …
Alprostadil injection attenuates coronary microembolization-induced myocardial injury through GSK-3β/Nrf2/HO-1 signaling-mediated apoptosis inhibition
Z Qin, B Kong, J Zheng, X Wang, L Li - Drug design, development …, 2020 - Taylor & Francis
Objective Coronary microembolization (CME) results in progressive contractile dysfunction
associated with cardiomyocyte apoptosis. Alprostadil injection improves microcirculation …
associated with cardiomyocyte apoptosis. Alprostadil injection improves microcirculation …
Protective effect of ligustrazine against myocardial ischaemia reperfusion in rats: the role of endothelial nitric oxide synthase
L Lv, SS Jiang, J Xu, JB Gong… - Clinical and Experimental …, 2012 - Wiley Online Library
The aim of the present study was to determine whether ligustrazine (2, 3, 5, 6‐
tetramethylpyrazine; TMP) exerts a cardioprotective effect during myocardial ischaemia …
tetramethylpyrazine; TMP) exerts a cardioprotective effect during myocardial ischaemia …
Ligustrazine exerts cardioprotection in animal models of myocardial ischemia/reperfusion injury: preclinical evidence and possible mechanisms
Q Zheng, Y Huang, P Zhu, Q Tong, X Bao… - Frontiers in …, 2018 - frontiersin.org
Ligustrazine (Lig) is one of the main effective components of Ligusticum Chuanxiong Hort,
which possesses a variety of biological activities in the cardiovascular system. Here, we …
which possesses a variety of biological activities in the cardiovascular system. Here, we …
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