Sirtuin 7 promotes non‑small cell lung cancer progression by facilitating G1/S phase and epithelial‑mesenchymal transition and activating AKT and ERK1/2 signaling
Y Zhao, X Ye, R Chen, Q Gao, D Zhao… - Oncology …, 2020 - spandidos-publications.com
Increasing evidence has indicated the roles of sirtuin 7 (SIRT7) in numerous human
cancers. However, the effects and the clinical significance of SIRT7 in human lung cancer is …
cancers. However, the effects and the clinical significance of SIRT7 in human lung cancer is …
[HTML][HTML] Upregulation of SIRT6 predicts poor prognosis and promotes metastasis of non-small cell lung cancer via the ERK1/2/MMP9 pathway
L Bai, G Lin, L Sun, Y Liu, X Huang, C Cao, Y Guo… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Abstract Sirtuin6 (SIRT6), a member of the sirtuins protein family, plays multiple complex
roles in cancer. Here, we report that elevated SIRT6 expression was correlated with …
roles in cancer. Here, we report that elevated SIRT6 expression was correlated with …
Retracted: Sirtuin 6 contributes to migration and invasion of osteosarcoma cells via the ERK1/2/MMP9 pathway
H Lin, Y Hao, Z Zhao, Y Tong - FEBS Open Bio, 2017 - Wiley Online Library
Dysregulation of sirtuin 6 (SIRT6) is actively involved in tumor progression. High levels of
SIRT6 have been associated with hepatocellular carcinoma and non‐small cell lung cancer …
SIRT6 have been associated with hepatocellular carcinoma and non‐small cell lung cancer …
[HTML][HTML] Silencing Sirtuin 6 induces cell cycle arrest and apoptosis in non-small cell lung cancer cell lines
V Krishnamoorthy, R Vilwanathan - Genomics, 2020 - Elsevier
Abstract Sirtuins (SIRT1–7), are NAD-dependent deacetylases and ADP-ribosyl
transferases, plays a major part in carcinogenesis. The previous report suggests that in …
transferases, plays a major part in carcinogenesis. The previous report suggests that in …
The expression and related clinical significance of SIRT3 in Non‐small‐cell lung cancer
GC Yang, BC Fu, DY Zhang, L Sun, W Chen… - Disease …, 2017 - Wiley Online Library
Objective. To examine the relationship between the Sirtuin‐3 (SIRT3) expression and the
clinical indicators/prognosis of patients with non‐small‐cell lung cancer (NSCLC). Methods …
clinical indicators/prognosis of patients with non‐small‐cell lung cancer (NSCLC). Methods …
[HTML][HTML] Sirtuin7 has an oncogenic potential via promoting the growth of cholangiocarcinoma cells
Accumulating evidence indicates that sirtuin7 (SIRT7) plays an oncogenic role in the main
types of liver cancer, hepatocellular carcinoma (HCC). Nevertheless, the clinical significance …
types of liver cancer, hepatocellular carcinoma (HCC). Nevertheless, the clinical significance …
Regulation of SIRT2 levels for human non-small cell lung cancer therapy
Seven Sirtuin family members (SIRT1-7), comprising a family of NAD+-dependent protein
deacetylases and ADP-ribosyltransferases, are key proteins that regulate multiple …
deacetylases and ADP-ribosyltransferases, are key proteins that regulate multiple …
SIRT1 expression is associated with poor prognosis of lung adenocarcinoma
C Li, L Wang, L Zheng, X Zhan, B Xu… - OncoTargets and …, 2015 - Taylor & Francis
Several studies have reported that the overexpression of Sirtuin 1 (SIRT1) was associated
with poor prognosis in various human cancers. However, little is known regarding the …
with poor prognosis in various human cancers. However, little is known regarding the …
[HTML][HTML] Sirtuin 7 plays an oncogenic role in human osteosarcoma via downregulating CDC4 expression
W Wei, ZX Jing, Z Ke, P Yi - American Journal of Cancer Research, 2017 - ncbi.nlm.nih.gov
It is still a controversy whether the role of Sirtuin 7 (SIRT7) is an oncogene or a tumor
suppressor gene in cancer as SIRT7 may have different functions in different types of …
suppressor gene in cancer as SIRT7 may have different functions in different types of …
MicroRNA-3666-induced suppression of SIRT7 inhibits the growth of non-small cell lung cancer cells
H Shi, Y Ji, D Zhang, Y Liu, P Fang - Oncology Reports, 2016 - spandidos-publications.com
Abstract Sirtuin7 (SIRT7) plays an important role in many cancer types, but its function in non-
small cell lung cancer (NSCLC) remains unclear. This study investigated the biological role …
small cell lung cancer (NSCLC) remains unclear. This study investigated the biological role …