Dosimetric factors associated with long-term dysphagia after definitive radiotherapy for squamous cell carcinoma of the head and neck

JJ Caudell, PE Schaner, RA Desmond… - International Journal of …, 2010 - Elsevier
PURPOSE: Intensification of radiotherapy and chemotherapy for head-and-neck cancer may
lead to increased rates of dysphagia. Dosimetric predictors of objective findings of long-term …

Phase III quality-of-life study results: impact on patients' quality of life to reducing xerostomia after radiotherapy for head-and-neck cancer—RTOG 97-09

J Fisher, C Scott, CW Scarantino, FG Leveque… - International Journal of …, 2003 - Elsevier
PURPOSE: To determine whether prevention of hyposalivation after curative radiotherapy
(RT) to the head and neck improves patients' quality of life (QOL). METHODS AND …

Novel approaches to improve the therapeutic index of head and neck radiotherapy: an analysis of data from the PARSPORT randomised phase III trial

F Buettner, AB Miah, SL Gulliford, E Hall… - Radiotherapy and …, 2012 - Elsevier
PURPOSE: Subjective xerostomia is a common side-effect following radiotherapy for the
treatment of head-and-neck cancer. Standard mean dose models previously used to model …

The potential benefit of swallowing sparing intensity modulated radiotherapy to reduce swallowing dysfunction: an in silico planning comparative study

HP van der Laan, MEMC Christianen, HP Bijl… - Radiotherapy and …, 2012 - Elsevier
PURPOSE: To apply recently developed predictive models for swallowing dysfunction to
compare the predicted probabilities of swallowing dysfunction for standard intensity …

Radiation-induced xerostomia: pathophysiology, prevention and treatment

SA Bhide, AB Miah, KJ Harrington, KL Newbold… - Clinical oncology, 2009 - Elsevier
Radiation-induced xerostomia is highly prevalent among patients treated for head and neck
cancers. Consequently, survivors experience associated long-term toxicities that may be …

Radiation‐induced xerostomia in patients with head and neck cancer: pathogenesis, impact on quality of life, and management

MS Chambers, AS Garden, MS Kies… - Head & Neck: Journal …, 2004 - Wiley Online Library
Background. Xerostomia is a common, debilitating complication of radiation therapy (RT) for
head and neck cancer. This article reviews the pathogenesis of radiation‐induced …

Intensity-modulated radiotherapy reduces radiation-induced morbidity and improves health-related quality of life: results of a nonrandomized prospective study using a …

MR Vergeer, PAH Doornaert, DHF Rietveld… - International Journal of …, 2009 - Elsevier
PURPOSE: The purpose of this study was to compare intensity-modulated radiation therapy
(IMRT) and three-dimensional conventional radiotherapy (3D-CRT) with regard to patient …

Evaluation of salivary gland function after treatment of head-and-neck tumors with intensity-modulated radiotherapy by quantitative pertechnetate scintigraphy

MW Münter, CP Karger, SG Hoffner, H Hof… - International Journal of …, 2004 - Elsevier
PURPOSE: To evaluate salivary gland function after inversely planned stereotactic intensity-
modulated radiotherapy (IMRT) for tumors of the head-and-neck region using quantitative …

Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma

ME Daly, YY Lieskovsky, T Pawlicki, J Yau… - Head & …, 2007 - Wiley Online Library
Background. Our aim was to correlate patterns of failure with target volume delineations in
patients with head and neck squamous cell carcinoma (HNSCC) treated with intensity …

Treatment planning constraints to avoid xerostomia in head-and-neck radiotherapy: an independent test of QUANTEC criteria using a prospectively collected dataset

V Moiseenko, J Wu, A Hovan, Z Saleh, A Apte… - International Journal of …, 2012 - Elsevier
PURPOSE: The severe reduction of salivary function (xerostomia) is a common complication
after radiation therapy for head-and-neck cancer. Consequently, guidelines to ensure …