The Stat3 inhibitor, S3I-201, downregulates lymphocyte activation markers, chemokine receptors, and inflammatory cytokines in the BTBR T+ Itpr3tf/J mouse model of …
Autism is a complex neurodevelopmental disorder with a high incidence rate. It is
characterized by deficits in communication, a lack of social skills, cognitive inflexibility, and …
characterized by deficits in communication, a lack of social skills, cognitive inflexibility, and …
[HTML][HTML] Neuronal correlates of asocial behavior in a BTBR T+Itpr3tf/J mouse model of autism
K Meyza, T Nikolaev, K Kondrakiewicz… - Frontiers in behavioral …, 2015 - frontiersin.org
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized, in part, by
an inability to adequately respond to social cues. Patients diagnosed with ASD are often …
an inability to adequately respond to social cues. Patients diagnosed with ASD are often …
Nrf2 activator, sulforaphane ameliorates autism-like symptoms through suppression of Th17 related signaling and rectification of oxidant-antioxidant imbalance in …
Autism is a neurodevelopmental disease which is characterized by its core behavioral
symptoms such as impairment in social interaction and stereotyped repetitive behavior …
symptoms such as impairment in social interaction and stereotyped repetitive behavior …
The Multi-Targeting Ligand ST-2223 with Histamine H3 Receptor and Dopamine D2/D3 Receptor Antagonist Properties Mitigates Autism-Like Repetitive Behaviors …
N Eissa, K Venkatachalam, P Jayaprakash… - International journal of …, 2021 - mdpi.com
Autism spectrum disorder (ASD) is a complex heterogeneous neurodevelopmental disorder
characterized by social and communicative impairments, as well as repetitive and restricted …
characterized by social and communicative impairments, as well as repetitive and restricted …
All‐trans‐retinoic acid ameliorates experimental allergic encephalomyelitis by affecting dendritic cell and monocyte development
XX Zhan, Y Liu, JF Yang, GY Wang, L Mu… - …, 2013 - Wiley Online Library
Experimental allergic encephalomyelitis (EAE) can be induced in animal models by injecting
the MOG35–55 peptide subcutaneously. Dendritic cells (DCs) that are located at the …
the MOG35–55 peptide subcutaneously. Dendritic cells (DCs) that are located at the …
The potent immunomodulatory compound VGX-1027 regulates inflammatory mediators in CD4+ T cells, which are concomitant with the prevention of neuroimmune …
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by
symptoms that include social communication impairments, interaction deficits, and repetitive …
symptoms that include social communication impairments, interaction deficits, and repetitive …
Impaired calcium signaling in astrocytes modulates autism spectrum disorder-like behaviors in mice
Q Wang, Y Kong, DY Wu, JH Liu, W Jie, QL You… - Nature …, 2021 - nature.com
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder. The
mechanisms underlying ASD are unclear. Astrocyte alterations are noted in ASD patients …
mechanisms underlying ASD are unclear. Astrocyte alterations are noted in ASD patients …
Behavioral assessments of BTBR T+ Itpr3tf/J mice by tests of object attention and elevated open platform: Implications for an animal model of psychiatric comorbidity in …
OY Chao, R Yunger, YM Yang - Behavioural brain research, 2018 - Elsevier
Autism spectrum disorders (ASD) are diagnosed based on the behavioral criteria of
impaired social interaction, defective communication and repetitive behaviors. Psychiatric …
impaired social interaction, defective communication and repetitive behaviors. Psychiatric …
Rho GTPase regulators and effectors in autism spectrum disorders: animal models and insights for therapeutics
D Guo, X Yang, L Shi - Cells, 2020 - mdpi.com
The Rho family GTPases are small G proteins that act as molecular switches shuttling
between active and inactive forms. Rho GTPases are regulated by two classes of regulatory …
between active and inactive forms. Rho GTPases are regulated by two classes of regulatory …
Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders
A Annamneedi, C Gora, A Dudas… - British Journal of …, 2023 - Wiley Online Library
Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two
core symptoms: deficits in social interaction and communication, and stereotyped …
core symptoms: deficits in social interaction and communication, and stereotyped …