[HTML][HTML] Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …
characterized by two core behavioral symptoms, namely impairments in social …
[HTML][HTML] Critical roles of serotonin-oxytocin interaction during the neonatal period in social behavior in 15q dup mice with autistic traits
M Nagano, T Takumi, H Suzuki - Scientific reports, 2018 - nature.com
Disturbance of neurotransmitters and neuromodulators is thought to underlie the
pathophysiology of autism spectrum disorder (ASD). Studies of 15q dup mouse models of …
pathophysiology of autism spectrum disorder (ASD). Studies of 15q dup mouse models of …
Adenosine A2A receptor deletion affects social behaviors and anxiety in mice: involvement of anterior cingulate cortex and amygdala
L López-Cruz, M Carbó-Gas, M Pardo, P Bayarri… - Behavioural Brain …, 2017 - Elsevier
Blockade of adenosine A 2A receptors can potentiate motivation to work for natural
reinforcers such as food. Conspecific interaction is a potent natural reinforcer in social …
reinforcers such as food. Conspecific interaction is a potent natural reinforcer in social …
Involvement of CD45 cells in the development of autism spectrum disorder through dysregulation of granulocyte-macrophage colony-stimulating factor, key …
Autism spectrum disorder (ASD) is a complex and multifactorial heterogeneous disorder.
Previous investigations have revealed the association between the immune system and …
Previous investigations have revealed the association between the immune system and …
[HTML][HTML] Heterozygous Disruption of Autism susceptibility candidate 2 Causes Impaired Emotional Control and Cognitive Memory
K Hori, T Nagai, W Shan, A Sakamoto, M Abe… - PLoS …, 2015 - journals.plos.org
Mutations in the Autism susceptibility candidate 2 gene (AUTS2) have been associated with
a broad range of psychiatric illnesses including autism spectrum disorders, intellectual …
a broad range of psychiatric illnesses including autism spectrum disorders, intellectual …
Beneficial effects of fingolimod on social interaction, CNS and peripheral immune response in the BTBR mouse model of autism
R De Simone, A Butera, M Armida, A Pezzola… - Neuroscience, 2020 - Elsevier
Abstract Autism Spectrum Disorders (ASD) are neurodevelopmental disorders characterized
by social communication deficits and repetitive/stereotyped behaviours. We evaluated the …
by social communication deficits and repetitive/stereotyped behaviours. We evaluated the …
Evidence supporting an altered immune response in ASD
J Mead, P Ashwood - Immunology letters, 2015 - Elsevier
Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by
deficits in social interactions, communication, and increased stereotypical repetitive …
deficits in social interactions, communication, and increased stereotypical repetitive …
[HTML][HTML] Simultaneous Blockade of Histamine H3 Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of …
Autism spectrum disorder (ASD) is a heterogenous neurodevelopmental disorder defined by
persistent deficits in social interaction and the presence of patterns of repetitive and …
persistent deficits in social interaction and the presence of patterns of repetitive and …
Retinoid X receptor agonists modulate Foxp3+ regulatory T cell and Th17 cell differentiation with differential dependence on retinoic acid receptor activation
H Takeuchi, A Yokota-Nakatsuma, Y Ohoka… - The Journal of …, 2013 - journals.aai.org
Retinoic acid (RA) enhances TGF-β–dependent differentiation of Foxp3+ inducible
regulatory T cells (iTregs) and inhibits Th17 differentiation by binding to the RA receptor …
regulatory T cells (iTregs) and inhibits Th17 differentiation by binding to the RA receptor …
[HTML][HTML] Impaired neurodevelopmental pathways in autism spectrum disorder: a review of signaling mechanisms and crosstalk
S Kumar, K Reynolds, Y Ji, R Gu, S Rai… - Journal of …, 2019 - Springer
Background The development of an autistic brain is a highly complex process as evident
from the involvement of various genetic and non-genetic factors in the etiology of the autism …
from the involvement of various genetic and non-genetic factors in the etiology of the autism …