Fascination by the mitochondria,“the colonial posterity of migrant prokaryocytes, probably
primitive bacteria that swam into ancestral precursors of our eukaryotic cells and stayed …

Oxidative stress is among the major causes of toxicity due to interaction of Reactive Oxygen
Species (ROS) with cellular macromolecules and structures and interference with signal …

The integrity of mitochondrial function is fundamental to cell life. The cell demands for
mitochondria and their complex integration into cell biology, extends far beyond the …

Reactive oxygen species (ROS) are series of chemical products originated from one or
several electron reductions of oxygen. ROS are involved in physiology and disease and can …

Mitochondria are traditionally known as the energy generating centers of cells. Electron flux
through the mitochondrial respiratory chain, an organized sequence of complex enzymes …

The reduction of oxygen to water proceeds via one electron at a time. In the mitochondrial
respiratory chain, Complex IV (cytochrome oxidase) retains all partially reduced …

Mitochondria are a quantitatively relevant source of reactive oxygen species (ROS) in the
majority of cell types. Here we review the sources and metabolism of ROS in this organelle …

Mitochondria in aerobic eukaryotic cells are both the site of energy production and the
formation of harmful species, such as radicals and other reactive oxygen species, known as …

Hypertension is a condition associated with oxidative stress, endothelial dysfunction, and
increased vascular resistance, representing probably both a cause and a consequence of …

Mitochondria are quantifiably the most important sources of superoxide (O2●−) and
hydrogen peroxide (H2O2) in mammalian cells. The overproduction of these molecules has …