Electrochemical and theoretical study on interaction between erlotinib and DNA

M Jovanović, K Nikolic, M Čarapić… - Journal of Pharmaceutical …, 2023 - Elsevier
A comprehensive investigation of tyrosine kinase inhibitor erlotinib (ERL) electrochemical
behavior and interaction with DNA was performed with the aim to clarify its redox …

Voltammetric studies on the interaction of ds-DNA with anti-cancer agents imatinib and erlotinib–Comparison of Au and Pt nanoparticle effects to drug-DNA complex …

DE Bayraktepe, C Yıldız, Z Yazan - Journal of Molecular Liquids, 2023 - Elsevier
The interactions of imatinib (IMA) and erlotinib (ERL) with calf-thymus double-stranded
deoxyribonucleic acid (ds-DNA) were studied by using monometallic (Au and Pt) and …

The redox mechanism investigation of non-small cell lung cancer drug: Erlotinib via theoretical and experimental techniques and its host–guest detection by β …

NK Bakirhan, TT Tok, SA Ozkan - Sensors and Actuators B: Chemical, 2019 - Elsevier
Erlotinib (ERL) is a tyrosine kinase inhibitor which prevents growing of cancer cells. The
electrochemical oxidation mechanism of ERL was studied in details using cyclic …

Interaction of anticancer drug methotrexate with DNA analyzed by electrochemical and spectroscopic methods

B Rafique, AM Khalid, K Akhtar, A Jabbar - Biosensors and Bioelectronics, 2013 - Elsevier
Electrochemical DNA biosensor was used to study the interaction of methotrexate (MTX)
with DNA immobilized on the bare surface of glassy carbon electrode (GCE). The binding …

Characterizing the binding interaction between erlotinib and calf thymus DNA in vitro using multi‐spectroscopic methodologies and viscosity measurement combined …

XJ Chen, BL Wang, KL Zhou, YY Lou, SB Kou… - …, 2019 - Wiley Online Library
The binding interaction between erlotinib (ELTN) and calf thymus DNA (ct‐DNA) was
characterized with the help of multi‐spectroscopic approaches, viscosity measurement and …

[HTML][HTML] Elucidation of DNA-eltrombopag binding: Electrochemical, spectroscopic and molecular docking techniques

S Cheraghi, P Şenel, B Dogan Topal, S Agar… - Biosensors, 2023 - mdpi.com
Eltrombopag is a powerful adjuvant anticancer drug used in treating MS (myelodysplastic
syndrome) and AML (acute myeloid leukemia) diseases. In this study, the interaction …

Investigation of the electrochemical interaction behavior of DNA with 5-fluorouracil derivatives

K Zhang, W Liu - International Journal of Electrochemical Science, 2011 - Elsevier
Although many 5-Fluorouracil derivatives have been synthesized and identified, there are
few reports on the interaction modes of different anti-carcinogen 5-Fluorouracil derivatives …

Development of the electrochemical, spectroscopic and molecular docking approaches toward the investigation of interaction between DNA and anti-leukemic drug …

R Nimal, DN Unal, C Erkmen, B Bozal-Palabiyik… - …, 2022 - Elsevier
This study examines the interaction between pyrimidine nucleoside analogue azacytidine,
an anti-leukemic drug, and DNA by employing electrochemical, UV–vis spectroscopy …

Computational studies on effects of Efavirenz as an anticancer drug on DNA: application in drug design

S Riahi, S Eynollahi, MR Ganjali, P Norouzi - International Journal of …, 2010 - Elsevier
This research is designed to further understand the physicochemical interaction between the
novel drug EFZ, and its biological receptor DNA. The ultimate goal is to design drugs that …

Four-way parallel factor analysis of voltammetric four-way dataset for monitoring the etoposide-DNA interaction with its binding constant determination

Z Yazan, DE Bayraktepe, E Dinç - Bioelectrochemistry, 2020 - Elsevier
In this paper, a novel strategy in the application of the parallel factor analysis (PARAFAC) to
a four-way voltammetric dataset was improved to evidence the interaction of etoposide …